To search the entire human genome for association is a novel and promising approach to
unravelling the genetic basis of complex genetic diseases. In these genome‐wide …

Motivation: The sequencing of the human genome has made it possible to identify an
informative set of> 1 million single nucleotide polymorphisms (SNPs) across the genome …

Genome-wide association study (GWAS) is a powerful study design to identify genetic
variants of a trait and, in particular, detect the association between common single …

Abstract Motivation: Although Genome Wide Association Studies (GWAS) genotype a very
large number of single nucleotide polymorphisms (SNPs), the data are often analyzed one …

Genome-wide association studies (GWAS) detect common genetic variants associated with
complex disorders. With their comprehensive coverage of common single nucleotide …

Single‐allele study designs, commonly used in genome‐wide association studies (GWAS)
as well as the more recently developed whole genome sequencing (WGS) studies, are a …

We have derived a versatile gene-based test for genome-wide association studies (GWAS).
Our approach, called VEGAS (versatile gene-based association study), is applicable to all …

Genomewide association studies are being conducted to unravel the genetic etiology of
complex human diseases. Because of cost constraints, these studies typically employ a two …

Many gene-based association tests have been proposed for genomewide association
studies (GWAS). However, the power of existing gene-based tests is... Genome-wide …

The variance component tests used in genome-wide association studies (GWAS) including
large sample sizes become computationally exhaustive when the number of genetic …