Sperm-mediated gene transfer (SMGT) has been long heralded as a faster and cheaper
alternative to more commonly used methods of producing transgenic animals. In this study …

Sperm-mediated gene transfer (SMGT) is a simple method for producing transgenic animals.
Due to the lack of repeatability in spermatozoa binding and internalization of exogenous …

The ability of rabbit spermatozoa to bind exogenous DNA during sperm‐mediated gene
transfer (SMGT) was tested in our study. Fresh collected semen, or fully capacitated sperm …

Sperm-mediated DNA transfer can be used to transfer exogenous DNA into the oocyte for
the production of transgenic animals. In spite of controversy in the literature, sperm-mediated …

Sperm-mediated gene transfer (SMGT) might become the most efficient and cost effective
technique to generate transgenic animals, which will significantly increase their application …

Spermatozoa have a spontaneous ability to take up exogenous DNA in a process regulated
by specific mechanisms. This ability has been used to carry exogenous DNA into oocytes …

Sperm-mediated gene transfer (SMGT) is a fast and low-cost method used to produce
transgenic animals. The objective of this study was to evaluate the effects of the …

Transgenic animals are produced primarily by microinjecting exogenous DNA into the male
pronuclei of a zygote. Microinjection is successful in mice but not efficient in farm animals …

Exogenous DNA localization and the frequency of spermatozoa carrying exogenous DNA
after sperm/DNA co-culture are key to a successful sperm mediated-gene transfer (SMGT) …

Transgenic mammals have been produced using sperm as vectors for exogenous DNA
(sperm-mediated gene transfer (SMGT)) in combination with artificial insemination. Our …