Deregulated transcription factors in cancer cell metabolisms and reprogramming

R Kant, RK Manne, M Anas, V Penugurti, T Chen… - Seminars in cancer …, 2022 - Elsevier
Metabolic reprogramming is an important cancer hallmark that plays a key role in cancer
malignancies and therapy resistance. Cancer cells reprogram the metabolic pathways to …

[HTML][HTML] Oncogenic regulation of tumor metabolic reprogramming

M Tarrado-Castellarnau, P de Atauri, M Cascante - Oncotarget, 2016 - ncbi.nlm.nih.gov
Abstract Development of malignancy is accompanied by a complete metabolic
reprogramming closely related to the acquisition of most of cancer hallmarks. In fact, key …

[HTML][HTML] Metabolic signaling to epigenetic alterations in cancer

JA Kim, YI Yeom - Biomolecules & therapeutics, 2018 - ncbi.nlm.nih.gov
Cancer cells reprogram cellular metabolism to support the malignant features of tumors,
such as rapid growth and proliferation. The cancer promoting effects of metabolic …

Metabolic reprogramming in cancer: Mechanisms and therapeutics

S Nong, X Han, Y Xiang, Y Qian, Y Wei, T Zhang… - MedComm, 2023 - Wiley Online Library
Cancer cells characterized by uncontrolled growth and proliferation require altered
metabolic processes to maintain this characteristic. Metabolic reprogramming is a process …

Metabolic codependencies in the tumor microenvironment

P Dey, AC Kimmelman, RA DePinho - Cancer Discovery, 2021 - AACR
Metabolic reprogramming enables cancer cell growth, proliferation, and survival. This
reprogramming is driven by the combined actions of oncogenic alterations in cancer cells …

Reciprocal regulation of metabolic reprogramming and epigenetic modifications in cancer

X Yu, R Ma, Y Wu, Y Zhai, S Li - Frontiers in Genetics, 2018 - frontiersin.org
Cancer cells reprogram their metabolism to meet their demands for survival and
proliferation. The metabolic plasticity of tumor cells help them adjust to changes in the …

Crosstalk between metabolic reprogramming and epigenetics in cancer: updates on mechanisms and therapeutic opportunities

T Ge, X Gu, R Jia, S Ge, P Chai… - Cancer …, 2022 - Wiley Online Library
Reversible, spatial, and temporal regulation of metabolic reprogramming and epigenetic
homeostasis are prominent hallmarks of carcinogenesis. Cancer cells reprogram their …

How cancer metabolism is tuned for proliferation and vulnerable to disruption

A Schulze, AL Harris - Nature, 2012 - nature.com
Cancer metabolism has received a substantial amount of interest over the past decade. The
advances in analytical tools have, along with the rapid progress of cancer genomics …

Cancer metabolism and carcinogenesis

J Yang, C Shay, NF Saba, Y Teng - Experimental Hematology & Oncology, 2024 - Springer
Metabolic reprogramming is an emerging hallmark of cancer cells, enabling them to meet
increased nutrient and energy demands while withstanding the challenging …

Metabolic reprogramming and cancer progression

B Faubert, A Solmonson, RJ DeBerardinis - Science, 2020 - science.org
BACKGROUND Metabolic reprogramming is a hallmark of malignancy first recognized a
century ago. In some cases, reprogrammed metabolic activities can be exploited to …