Conjugative plasmids enable the maintenance of low cost non-transmissible plasmids

M Werisch, U Berger, TU Berendonk - Plasmid, 2017 - Elsevier
Some plasmids can be transferred by conjugation to other bacterial hosts. But almost half of
the plasmids are non-transmissible. These plasmid types can only be transmitted to the …

Plasmid Costs Explain Plasmid Maintenance, Irrespective of the Nature of Compensatory Mutations

JS Rebelo, CPF Domingues, F Dionisio - Antibiotics, 2023 - mdpi.com
Conjugative plasmids often carry virulence and antibiotic-resistant genes. Therefore,
understanding the behavior of these extra-chromosomal DNA elements gives insights into …

Plasmid interactions can improve plasmid persistence in bacterial populations

JA Gama, R Zilhão, F Dionisio - Frontiers in Microbiology, 2020 - frontiersin.org
It is difficult to understand plasmid maintenance in the absence of selection and theoretical
models predict the conditions for plasmid persistence to be limited. Plasmid-associated …

The evolution of a conjugative plasmid and its ability to increase bacterial fitness

F Dionisio, IC Conceicao, ACR Marques… - Biology …, 2005 - royalsocietypublishing.org
Conjugative plasmids are extra-chromosomal DNA elements that are capable of horizontal
transmission and are found in many natural isolated bacteria. Although plasmids may carry …

Plasmids increase the competitive ability of plasmid-bearing cells even when transconjugants are poor donors, as shown by computer simulations

JS Rebelo, CPF Domingues, T Nogueira, F Dionisio - Microorganisms, 2023 - mdpi.com
Bacterial cells often suffer a fitness cost after conjugative plasmids' entry because these cells
replicate slower than plasmid-free cells. Compensatory mutations may appear after tens of …

Plasmid viability depends on the ecological setting of hosts within a multiplasmid community

C Given, R Penttinen, M Jalasvuori - Microbiology Spectrum, 2022 - Am Soc Microbiol
Plasmids are extrachromosomal genetic elements, some of which disperse horizontally
between different strains and species of bacteria. They are a major factor in the …

Harmful behaviour through plasmid transfer: a successful evolutionary strategy of bacteria harbouring conjugative plasmids

CPF Domingues, JS Rebelo… - … of the Royal …, 2022 - royalsocietypublishing.org
Conjugative plasmids are extrachromosomal mobile genetic elements pervasive among
bacteria. Plasmids' acquisition often lowers cells' growth rate, so their ubiquity has been a …

Plasmid persistence: costs, benefits, and the plasmid paradox

AC Carroll, A Wong - Canadian journal of microbiology, 2018 - cdnsciencepub.com
Plasmids are extrachromosomal DNA elements that can be found throughout bacteria, as
well as in other domains of life. Nonetheless, the evolutionary processes underlying the …

The evolution of plasmid stability: Are infectious transmission and compensatory evolution competing evolutionary trajectories?

JPJ Hall, MA Brockhurst, C Dytham, E Harrison - Plasmid, 2017 - Elsevier
Conjugative plasmids are widespread and play an important role in bacterial evolution by
accelerating adaptation through horizontal gene transfer. However, explaining the long-term …

Characterizing conjugative plasmids from an antibiotic-resistant dataset for use as broad-host delivery vectors

HG Loyola Irizarry, IL Brito - Frontiers in Microbiology, 2023 - frontiersin.org
Human microbiome engineering is increasingly proposed as a way to modulate health
outcomes. However, one of the current limitations to engineering microbial communities in …