Hepsin is an integral membrane protein that may participate in cell growth and in
maintaining proper cell morphology and is overexpressed in a number of primary tumors …

Hepsin, a putative membrane-bound serine protease, was originally identified as a human
liver cDNA clone (Leytus, SP, Loeb, KR, Hagen, FS, Kurachi, K., and Davie, EW (1988) …

Hepsin is a transmembrane serine protease implicated in many biological processes,
including hepatocyte growth, urinary protein secretion, auditory nerve development, and …

Hepsin is a serine protease that is widely expressed in different tissues and cell types, most
prominently in the normal liver and kidney. Overexpression of hepsin has been associated …

Hepsin is a type II transmembrane serine protease that is expressed in normal liver, and at
lower levels in kidney, pancreas, and testis. Several studies have shown that hepsin mRNA …

Hepsin is a membrane-anchored, trypsin-like serine protease with prominent expression in
the human liver and tumours of the prostate and ovaries. To better understand the biological …

Extracellular proteases mediate the digestion of neighboring extracellular matrix
components in initial tumor growth, allow shedding or desquamation of tumor cells into the …

Background/Aims: Hepsin is a type II transmembrane protein predominantly expressed in
the liver and has been implicated in participation in blood coagulation pathway and …

The majority of cancer-related deaths are associated with metastasis; however, little is
known about the mechanisms of this process. Hepsin is a cell surface serine protease that is …

Hepsin is a type II transmembrane serine protease overexpressed in the majority of human
prostate cancers. We recently demonstrated that hepsin promotes prostate cancer …