Platform trials are generally regarded as an innovative approach to address clinical
valuation of early stage candidates, regardless of modality as the evidence evolves. As a …

Motivation Platform designs-master protocols that allow for new treatment arms to be added
over time-have gained considerable attention in recent years. Between 2001 and 2019, 16 …

Platform trials bring the promise of making clinical research more efficient and more patient
centric. While their use has become more widespread, including their prominent role during …

The shift to electronic initiaitives over the past 18 months is apparent. In fact, it seems we
can't blink our eyes without hearing about COVID's digital impact these days. When it comes …

For the development of coronavirus disease 2019 (COVID‐19) drugs during the ongoing
pandemic, speed is of essence whereas quality of evidence is of paramount importance …

For the past few years, platform trials have experienced a significant increase, recently
amplified by the COVID-19 pandemic. The implementation of a platform trial is particularly …

Platform trials are a type of randomized clinical trial that allow simultaneous comparison of
multiple intervention groups against a single control group that serves as a common control …

Issue Recently, innovative clinical trial designs have been proposed, which have the
potential to revolutionize clinical research. Whereas classical trials mostly evaluate only one …

Background In response to the COVID-19 global pandemic, multiple platform trials were
initiated to accelerate evidence generation of potential therapeutic interventions. Given a …

Clinical trials are a fundamental tool in evaluating the safety and efficacy of new drugs,
medical devices, and health system interventions. Clinical trial visits generally involve …