[HTML][HTML] Analysis of plasma proteins involved in inflammation, immune response/complement system, and blood coagulation upon admission of COVID-19 patients to …

DC Di Flora, A Dionizio, HABS Pereira, TF Garbieri… - Cells, 2023 - mdpi.com
The development of new approaches allowing for the early assessment of COVID-19 cases
that are likely to become critical and the discovery of new therapeutic targets are urgently …

[HTML][HTML] Proteomic analysis identifies a signature of disease severity in the plasma of COVID-19 pneumonia patients associated to neutrophil, platelet and complement …

F Ciccosanti, M Antonioli, A Sacchi, S Notari, A Farina… - Clinical proteomics, 2022 - Springer
Most patients infected with SARS-CoV-2 display mild symptoms with good prognosis, while
20% of patients suffer from severe viral pneumonia and up to 5% may require intensive care …

Longitudinal plasma proteomics analysis reveals novel candidate biomarkers in acute COVID-19

Y Mohammed, DR Goodlett, MP Cheng… - Journal of proteome …, 2022 - ACS Publications
The host response to COVID-19 pathophysiology over the first few days of infection remains
largely unclear, especially the mechanisms in the blood compartment. We report on a …

[HTML][HTML] Cytokine elevation in severe COVID-19 from longitudinal proteomics analysis: comparison with sepsis

T Ebihara, H Matsumoto, T Matsubara… - Frontiers in …, 2022 - frontiersin.org
Introduction Coronavirus disease 2019 (COVID-19) is a new viral disease. Uncontrolled
inflammation called “cytokine storm” is reported to contribute to disease pathogenesis as …

[HTML][HTML] Mapping the serum proteome of COVID-19 patients; guidance for severity assessment

E Nuñez, I Orera, L Carmona-Rodríguez, JR Paño… - Biomedicines, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), whose outbreak in 2019 led to an ongoing pandemic with …

[HTML][HTML] Analysis of altered level of blood-based biomarkers in prognosis of COVID-19 patients

MR Shrestha, A Basnet, B Tamang, S Khadka… - PLoS …, 2023 - journals.plos.org
Introduction Immune and inflammatory responses developed by the patients with
Coronavirus Disease 2019 (COVID-19) during rapid disease progression result in an altered …

[HTML][HTML] Biomarker profiles associated with COVID-19 severity and mortality

S Sánchez-Díez, C Gómez-Ollés, MJ Cruz… - Current Issues in …, 2023 - mdpi.com
Introduction: The aim of this study was to analyze biomarkers that might predict the severity
and progression of the SARS-CoV-2 infection, both in the acute phase and after recovery …

Alterations in the plasma proteome induced by SARS-CoV-2 and MERS-CoV reveal biomarkers for disease outcomes for COVID-19 patients

A Alaiya, A Alshukairi, Z Shinwari… - Journal of …, 2021 - Taylor & Francis
Purpose This study aimed to understand the pathophysiology of host responses to infections
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/(COVID-19) and …

[HTML][HTML] Proteomic profiling reveals a distinctive molecular signature for critically ill COVID-19 patients compared with asthma and chronic obstructive pulmonary …

Z Zhang, F Lin, F Liu, Q Li, Y Li, Z Zhu, H Guo… - International Journal of …, 2022 - Elsevier
Objective The mortality rate for critically ill COVID-19 cases was more than 80%.
Nonetheless, research about the effect of common respiratory diseases on critically ill …

[HTML][HTML] Sera proteomic features of active and recovered COVID-19 patients: potential diagnostic and prognostic biomarkers

L Leng, M Li, W Li, D Mou, G Liu, J Ma… - Signal transduction and …, 2021 - nature.com
The early diagnosis and prognosis of COVID-19 remain major challenges. At present, there
are few studies focusing on the changes of sera proteome between active and recovered …