Cells of the developing human brain are affected by the progressive acquisition of genetic
and epigenetic alterations that have been reported to contribute to somatic mosaicism in the …

The hominid-specific non-LTR retrotransposon termed SINE VNTR Alu (SVA) is the
youngest of the transposable elements in the human genome. The propagation of the most …

Active retrotransposons in the human genome (L1, Alu and SVA elements) can create
genomic mobile element insertions (MEIs) in both germline and somatic tissue. Specific …

The SVA family of hominid-specific non-LTR retrotransposon comprises the youngest group
of transposable elements in the human genome. The propagation of the most ancient SVA …

Transposable elements (TEs) are repetitive elements which make up around 45% of the
human genome. A class of TEs, known as SINE-VNTR-Alu (SVA), demonstrate the capacity …

Abstract SINE-VNTR-Alu (SVA) retrotransposons are evolutionarily young and still-active
transposable elements (TEs) in the human genome. Several pathogenic SVA insertions …

The healthy human brain is a mosaic of varied genomes. Long interspersed element-1
(LINE-1 or L1) retrotransposition is known to create mosaicism by inserting L1 sequences …

Retrotransposable elements (RTEs) have actively multiplied over the past 80 million years of
primate evolution, and as a consequence, such elements collectively occupy∼ 40% of the …

Non-allelic recombination between homologous repetitive elements contributes to evolution
and human genetic disorders. Here, we combine short-and long-DNA read sequencing of …

Background Retrotransposons are a major component of the human genome constituting as
much as 45%. The hominid specific SINE-VNTR-Alus are the youngest of these elements …