duced in man and other mammals solely from the catabolism of heme,· and that 1 mole of
CO is produced and rapidly excreted intact in the breath for every mole of heme degraded …

IiT9uDu': TIa'Previous studies have demonstrated that endogenously-prcduced carbon
monoxide in'mammals arises solely from the alpha-imethene brid90 carbon atom c of …

In the late 1940's, Sjö strand demonstrated the presence of carbon monoxide in the expired
air of the normal, non-smoking man (1). By in vivo and in vitro techniques he was able to …

It has now been over 20 years since the first demonstration that CO is endog enously
produced in normal man (Sjostrand 1). Methods of accurately measuring CO production in …

Measurements of pulmonary carbon monoxide (CO) excretion can be used as a quantitative
indicator of heme turnover. We determined whether a diurnal variation of heme turnover …

RODKEY, IT. LEE, HAROLD A. COLLISON, AND JOHN II OWEAL. Carbon monoxide and
methane production in rats, guinea@ gs, und gel-m-free ruts. J. Appl. Physiol. 33 (2): 256 …

During the Second World War, Sweden was obliged to use p: roducer gas in place of
gasoline for autolIDbile propulsion, and ID3Ily cases of carbon IIDnoxide (CO) poisoning …

Even though the heme degradation pathway consists of only two reactions, it and its major
enzyme (ie HO), nonetheless, impact other processes not only through the removal of …

The existence of small amounts of a combustible gas in the blood was! kst demonstrated by
Grehantl on dogs in 1894. The gas was supposed by de Saint-Martin2 and Nicloux3 to be …

Dogs anesthetized with pentobarbital were shown to produce carbon monoxide at an
average rate of 0.21±(SD) 0.05 ml per hour. After intravenous injection of erythrocytes …