Fc-modified SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models

M Takeshita, H Fukuyama, K Kamada, T Matsumoto… - bioRxiv, 2022 - biorxiv.org
The use of therapeutic neutralizing antibodies against SARS-CoV-2 infection has been
highly effective. However, there remain few practical antibodies against viruses that are …

Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models

M Takeshita, H Fukuyama, K Kamada, T Matsumoto… - Iscience, 2022 - cell.com
The use of therapeutic neutralizing antibodies against SARS-CoV-2 infection has been
highly effective. However, there remain few practical antibodies against viruses that are …

Fc-independent neutralization of SARS-CoV-2 by recombinant human monoclonal antibodies

T Noy-Porat, A Edri, R Alcalay, E Makdasi, D Gur… - bioRxiv, 2021 - biorxiv.org
The use of passively-administered neutralizing antibodies is a promising approach for the
prevention and treatment of SARS-CoV-2 infection. Antibody-mediated protection may …

Potent neutralizing anti-SARS-CoV-2 human antibodies cure infection with SARS-CoV-2 variants in hamster model

M Imbrechts, W Maes, L Ampofo, N Van den Berghe… - Iscience, 2022 - cell.com
Treatment with neutralizing monoclonal antibodies (mAbs) against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) contributes to COVID-19 management …

[HTML][HTML] Characterization of neutralizing antibodies from a SARS-CoV-2 infected individual

E Seydoux, LJ Homad, AJ MacCamy, KR Parks… - BioRxiv, 2020 - ncbi.nlm.nih.gov
B cells specific for the SARS-CoV-2 S envelope glycoprotein spike were isolated from a
COVID-19-infected subject using a stabilized spike-derived ectodomain (S2P) twenty-one …

[HTML][HTML] A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model

J Kreye, SM Reincke, HC Kornau, E Sánchez-Sendin… - bioRxiv - ncbi.nlm.nih.gov
The emergence of SARS-CoV-2 led to pandemic spread of coronavirus disease 2019
(COVID-19), manifesting with respiratory symptoms and multi-organ dysfunction. Detailed …

Discovery and development of human SARS-CoV-2 neutralizing antibodies using an unbiased phage display library approach

X Cao, J Maruyama, H Zhou, L Kerwin, R Sattler… - bioRxiv, 2020 - biorxiv.org
ABSTRACT SARS-CoV-2 neutralizing antibodies represent an important component of the
ongoing search for effective treatment of and protection against COVID-19. We report here …

SARS-CoV-2 neutralization and protection of hamsters via nasal administration of a humanized neutralizing antibody

M Lebedin, N Petrovsky, K Tabynov, K Tabynov… - bioRxiv, 2024 - biorxiv.org
Monoclonal antibodies are widely used for the treatment of infectious human diseases,
including COVID-19. Since the start of the pandemic, eight monoclonal antibodies against …

SARS-CoV-2 neutralizing antibodies for COVID-19 prevention and treatment

D Li, GD Sempowski, KO Saunders… - Annual review of …, 2022 - annualreviews.org
Prophylactic and therapeutic drugs are urgently needed to combat coronavirus disease
2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses

Y Chen, X Zhao, H Zhou, H Zhu, S Jiang… - Nature Reviews …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …