Antioxidative treatment diminishes ethanol‐induced congenital malformations in the rat

P Wentzel, U Rydberg… - Alcoholism: Clinical and …, 2006 - Wiley Online Library
Background: Intrauterine exposure to ethanol causes embryonic and fetal growth retardation
and maldevelopment. Oxidative stress in mother and offspring has been suggested to be …

Ethanol-induced fetal dysmorphogenesis in the mouse is diminished by high antioxidative capacity of the mother

P Wentzel, UJ Eriksson - Toxicological Sciences, 2006 - academic.oup.com
Intrauterine exposure to ethanol causes embryonic and fetal maldevelopment. Oxidative
stress in mother and offspring has been suggested to be part of the teratogenic mechanism …

In utero ethanol exposure elicits oxidative stress in the rat fetus

GI Henderson, BG Devi, A Perez… - Alcoholism: Clinical …, 1995 - Wiley Online Library
Prior studies in our laboratory have shown that exposure of cultured fetal rat hepatocytes to
ethanol (E) blocks epidermal growth factor‐dependent replication and that this is paralleled …

Genetic Influence on Dysmorphogenesis in Embryos From Different Rat Strains Exposed to Ethanol in Vivo and in Vitro

P Wentzel, UJ Eriksson - Alcoholism: Clinical and Experimental …, 2008 - Wiley Online Library
Background: The aim was to investigate the susceptibility of embryos from 2 rat strains (U
and H) to a 48 hours ethanol exposure in early pregnancy, both in vivo and in vitro. Methods …

Antioxidants and fetal protection against ethanol teratogenicity: I. Review of the experimental data and implications to humans

R Cohen-Kerem, G Koren - Neurotoxicology and teratology, 2003 - Elsevier
Ethanol is the most common human teratogen, and heavy drinking during pregnancy can
result in serious adverse outcomes to the fetus. The cellular mechanisms by which ethanol …

Prenatal exposure to ethanol in rats: effects on liver energy level and antioxidant status in mothers, fetuses, and newborns

G Addolorato, A Gasbarrini, S Marcoccia, M Simoncini… - Alcohol, 1997 - Elsevier
The fetal alcohol syndrome is a clinical conndition that affects newborns from alcoholic
mothers. It is not clear, however, whether ethanol consumption during gestation can affect …

Ethanol‐induced teratogenesis: free radical damage as a possible mechanism

LE Kotch, SY Chen, KK Sulik - Teratology, 1995 - Wiley Online Library
To investigate the possibility of a free radical mechanism for ethanol‐induced teratogenesis,
gestational day 8 mouse embryos were exposed for 6 hr in whole embryo culture to a …

The preventive effect of oral EGCG in a fetal alcohol spectrum disorder mouse model

L Long, Y Li, YD Wang, QY He, M Li… - Alcoholism: Clinical …, 2010 - Wiley Online Library
Background: Fetal alcohol spectrum disorder (FASD) is a challenging public health problem.
Previous studies have found an association between FASD and oxidative stress. In the …

Angiogenesis is repressed by ethanol exposure during chick embryonic development

G Wang, S Zhong, S Zhang, Z Ma… - Journal of Applied …, 2016 - Wiley Online Library
It is now known that excess alcohol consumption during pregnancy can cause fetal alcohol
syndrome to develop. However, it is not known whether excess ethanol exposure could …

Neurotoxic effects of alcohol and acetaldehyde during embryonic development

R Da Lee, S Mi An, S Sun Kim… - Journal of Toxicology …, 2005 - Taylor & Francis
Alcohol drinking during pregnancy results in abnormal fetal development, including fetal
alcohol syndrome (FAS) in humans and experimental animals. FAS is characterized by two …