Peering into the field of Alzheimer's disease (AD), the outsider realizes that many of the
therapeutic strategies tested (in animal models) have been successful. One also may notice …

Alzheimer disease (AD) prevention trials hold the promise to delay or prevent cognitive
decline and dementia onset by intervening before significant neuronal damage occurs. In …

Worldwide multidisciplinary translational research has led to a growing knowledge of the
genetics and molecular pathogenesis of Alzheimer's disease (AD) indicating that …

In recent years the amyloid cascade hypothesis of Alzheimer disease (AD) has been
increasingly referred to as the amyloid β protein (Aβ) cascade hypothesis. This subtle …

Alzheimerβs disease (AD) is a multifactorial neurodegenerative disorder with several target
proteins contributing to its aetiology. Pathological, genetic, biochemical, and modeling …

Abstract Alzheimer's disease (AD), the most prevalent neurodegenerative disease in the
elderly population, is characterized by progressive cognitive decline and pathological …

Alzheimer's disease (AD) is a highly prevalent neurodegenerative disorder characterized by
a progressive loss of cognition and the presence of two hallmark lesions, senile plaques …

Basic research advances in recent years have furthered our understanding of the natural
history of Alzheimer's disease (AD). It is now recognized that pathophysiological changes …

Damage or loss of brain cells and impaired neurochemistry, neurogenesis, and synaptic and
nonsynaptic plasticity of the brain lead to dementia in neurodegenerative diseases, such as …

Amyloid beta (Aβ) is an intricate molecule that interacts with several biomolecules and/or
produces insoluble assemblies and eventually the nonphysiological depositions of its …