Bioinformatics-based investigation on the genetic influence between SARS-CoV-2 infections and idiopathic pulmonary fibrosis (IPF) diseases, and drug repurposing

MA Islam, MK Kibria, MB Hossen, MS Reza… - Scientific Reports, 2023 - nature.com
Some recent studies showed that severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infections and idiopathic pulmonary fibrosis (IPF) disease might stimulate each other …

An approach combining bioinformatics and machine learning to identify eight autophagyrelated biomarkers and construct molecular mechanisms underlying COVID …

C Yu, FJ Zhang, LL Zhang, DX Xian… - … Review for Medical …, 2022 - search.ebscohost.com
OBJECTIVE: A lack of objective biomarkers is preventing the screening and diagnosis of
COVID-19 combined with major depression disorder (COVID-19-MDD). The purpose of this …

Integrative bioinformatics analysis reveals STAT2 as a novel biomarker of inflammation-related cardiac dysfunction in atrial fibrillation

C Li, G Li, S Tu, X Bai, H Yuan - Open Medicine, 2023 - degruyter.com
Atrial fibrillation (AF) is a common critical cause of stroke and cardiac dysfunction worldwide
with lifetime risks. Viral infection and inflammatory response with myocardial involvement …

[PDF][PDF] Impact of Obstructive Sleep Apnea on Health Outcomes in Veterans Hospitalized with COVID-19 Infection

B Prasad, A Mechineni, S Talugula… - Annals of the …, 2024 - atsjournals.org
Methods We retrospectively analyzed patients in the Jesse Brown Veteran Affairs Medical
Center (JBVAMC) COVID-19 registry in Chicago, IL, United States (11). Data were obtained …

Comparative transcriptome analyses reveal genes associated with SARS-CoV-2 infection of human lung epithelial cells

DS Chandrashekar, M Athar, U Manne… - Scientific Reports, 2021 - nature.com
During 2020, understanding the molecular mechanism of SARS-CoV-2 infection (the cause
of COVID-19) became a scientific priority due to the devastating effects of the COVID-19 …

Identification of key genes and immune infiltration modulated by CPAP in obstructive sleep apnea by integrated bioinformatics analysis

C Fan, S Huang, C Xiang, T An, Y Song - Plos one, 2021 - journals.plos.org
Patients with obstructive sleep apnea (OSA) experience partial or complete upper airway
collapses during sleep resulting in nocturnal hypoxia-normoxia cycling, and continuous …

[PDF][PDF] Potential core genes associated with COVID-19 identified via weighted gene co-expression network analysis

C Wu, Z Wu, Y Chen, X Huang, B Tian - Swiss Medical Weekly, 2022 - smw.ch
AIMS: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel virus
belonging to the Coronaviridae family that causes coronavirus disease (COVID-19). This …

Obstructive Sleep Apnea as a Risk Factor for COVID-19 Severity—The Gut Microbiome as a Common Player Mediating Systemic Inflammation via Gut Barrier …

S Mashaqi, R Kallamadi, A Matta, SF Quan, SI Patel… - Cells, 2022 - mdpi.com
The novel corona virus that is now known as (SARS-CoV-2) has killed more than six million
people worldwide. The disease presentation varies from mild respiratory symptoms to acute …

Exploring shared pathways and the shared biomarker ERRFI1 in Obstructive sleep apnoea and atherosclerosis using integrated bioinformatics analysis

B Chen, L Dong, J Zhang, Y Hao, W Chi, D Song - Scientific Reports, 2023 - nature.com
Obstructive sleep apnea (OSA) is an upper airway disorder occurring during sleep and is
associated with atherosclerosis (AS). AS is a cardiovascular disease caused by …

Identification and validation of predictive factors for progression to severe COVID-19 pneumonia by proteomics

B Di, H Jia, OJ Luo, F Lin, K Li, Y Zhang… - Signal transduction and …, 2020 - nature.com
Recent study showed that around 80% of coronavirus disease-19 (COVID-19) patients are
moderate cases who will recover with or without conventional treatment, while the remaining …