Rheumatoid arthritis (RA) is an autoimmune disease that results in a chronic systemic
inflammation. A few genetic epidemiologic studies found a potential association between …

Abstract Context The c. 677 C> T and c. 1298 A> C polymorphisms of
methylenetatrahydrofolate reductase (MTHFR) gene and c. 3435 C> T polymorphism of ATP …

Methylenetetrahydrofolatereductase (MTHFR) is an important enzyme involved in folate
metabolism and DNA synthesis. Although a number of studies have examined the …

Rheumatoid arthritis (RA) is the most common autoimmune rheumatic disease, in which an
epigenetic implication in the disease etiopathogenesis has been noted. Here in this meta …

Methotrexate (MTX) is the most used drug in rheumatoid arthritis (RA) treatment. However, it
shows variability in clinical response, which is explained by an association with genetic …

The aim of our study was to conduct a meta-analysis to assess whether combined evidence
shows associations between C677T and A1298C polymorphisms of …

Rheumatoid arthritis (RA) is an autoimmune disease which has a significant socio-economic
impact. The aim of the current study was to investigate eight candidate RA susceptibility loci …

Some single-nucleotide polymorphisms (SNPs) might be predictive of methotrexate (MTX)
therapeutic outcome in rheumatoid arthritis (RA). The aim of this study was to determine …

Background: Rheumatoid arthritis is a widely prevalent autoimmune disorder with suggested
genetic predisposition. Objectives: The aim of this study is to detect the pattern of genetic …

Rheumatoid arthritis (RA) is a common illness of global significance for public health.
Methotrexate (MTX) is the most broadly used disease-modifying antirheumatic drug for the …