A long-held goal in sequencing has been to use a voltage-biased nanoscale pore in a
membrane to measure the passage of a linear, single-stranded (ss) DNA or RNA molecule …

Sequencing a single molecule of deoxyribonucleic acid (DNA) using a nanopore is a
revolutionary concept because it combines the potential for long read lengths (> 5 kbp) with …

DNA sequencing methods based on nanopores could potentially represent a low-cost and
high-throughput pathway to practical genomics, by replacing current sequencing methods …

A nanopore-based device provides single-molecule detection and analytical capabilities
that are achieved by electrophoretically driving molecules in solution through a nano-scale …

Nanopore DNA sequencing is limited by low base-calling accuracy. Improved base-calling
accuracy has so far relied on specialized base-calling algorithms, different nanopores and …

Much more than ever, nucleic acids are recognized as key building blocks in many of lifeʼs
processes, and the science of studying these molecular wonders at the single-molecule …

Nanopore-based DNA analysis is a single-molecule technique with revolutionary potential. It
promises to carry out a range of analyses, orders of magnitude faster than current methods …

Nanopore sequencing has the potential to become a direct, fast, and inexpensive DNA
sequencing technology. The simplest form of nanopore DNA sequencing utilizes the …

Solid-state nanopores have emerged as possible candidates for next-generation DNA
sequencing devices. In such a device, the DNA sequence would be determined by …

Voltage biased solid-state nanopores are used to detect and characterize individual single
stranded DNA molecules of fixed micrometer length by operating a nanopore detector at pH …