Natural and Recombinant SARS-CoV-2 Isolates Rapidly Evolve In Vitro to Higher Infectivity through More Efficient Binding to Heparan Sulfate and Reduced S1/S2 …

N Shiliaev, T Lukash, O Palchevska… - Journal of …, 2021 - Am Soc Microbiol
One of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virulence factors
is the ability to interact with high affinity to the ACE2 receptor, which mediates viral entry into …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): a global pandemic and treatment strategies

A Sharma, S Tiwari, MK Deb, JL Marty - International journal of antimicrobial …, 2020 - Elsevier
The emergence and rapid spread of coronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a potentially fatal disease …

A comprehensive review about SARS-CoV-2

SKM Haque, O Ashwaq, A Sarief… - Future …, 2020 - Future Medicine
The coronavirus disease (COVID-19) was first identified in China, December 2019. Since
then, it has spread the length and breadth of the world at an unprecedented, alarming rate …

COVID-19 Vaccine: A comprehensive status report

SP Kaur, V Gupta - Virus research, 2020 - Elsevier
The current COVID-19 pandemic has urged the scientific community internationally to find
answers in terms of therapeutics and vaccines to control SARS-CoV-2. Published …

SARS-CoV-2: An update on potential antivirals in light of SARS-CoV antiviral drug discoveries

HA Elshabrawy - Vaccines, 2020 - mdpi.com
Coronaviruses (CoVs) are a group of RNA viruses that are associated with different
diseases in animals, birds, and humans. Human CoVs (HCoVs) have long been known to …

Insights of severe acute respiratory syndrome coronavirus (SARS-CoV-2) pandemic: a current review

J Choudhary, S Dheeman, V Sharma, P Katiyar… - Biological procedures …, 2021 - Springer
COVID-19, a pandemic of the 21st century caused by novel coronavirus SARS-CoV-2 was
originated from China and shallowed world economy and human resource. The medical …

Increasing host cellular receptor—angiotensin‐converting enzyme 2 expression by coronavirus may facilitate 2019‐nCoV (or SARS‐CoV‐2) infection

MW Zhuang, Y Cheng, J Zhang… - Journal of medical …, 2020 - Wiley Online Library
The ongoing outbreak of a new coronavirus (2019‐nCoV, or severe acute respiratory
syndrome coronavirus 2 [SARS‐CoV‐2]) has caused an epidemic of the acute respiratory …

SARS-CoV-2/COVID-19 and advances in developing potential therapeutics and vaccines to counter this emerging pandemic

AA Rabaan, SH Al-Ahmed, R Sah, R Tiwari… - Annals of Clinical …, 2020 - Springer
A novel coronavirus (SARS-CoV-2), causing an emerging coronavirus disease (COVID-19),
first detected in Wuhan City, Hubei Province, China, which has taken a catastrophic turn with …

Emerging SARS-CoV-2 variants and impact in global vaccination programs against SARS-CoV-2/COVID-19

CE Gómez, B Perdiguero, M Esteban - Vaccines, 2021 - mdpi.com
The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants
in different continents is causing a major concern in human global health. These variants …

[HTML][HTML] Severe respiratory SARS-CoV2 infection: Does ACE2 receptor matter?

F Perrotta, MG Matera, M Cazzola, A Bianco - Respiratory medicine, 2020 - Elsevier
SARS-CoV-2 is a novel virus of the Coronaviridiae family that represents a major global
health issue. Mechanisms implicated in virus/host cells interaction are central for cell …