Background Hemophagocytic syndrome (HPS) is a severe hyperinflammatory disease,
whose diagnosis is based on the HLH-2004 criteria. In secondary forms of HLH (sHLH), the …

Abstract Coronavirus disease 2019 (COVID‐19) infection causes a variety of
extrapulmonary complications in pediatric patients. Multisystem inflammatory syndrome and …

Background Secondary haemophagocytic lymphohistiocytosis (sHLH) is characterised by a
hyper activation of immune system that leads to multiorgan failure. It is suggested that …

In most cases, COVID-19 has a favorable outcome. However, the risk of developing critical
forms of the disease, including secondary hemophagocytic lymphohistiocytosis–HLH …

IMPORTANCE COVID-19-infected pneumonia patients with severe immune abnormalities
and risk of cytokine release syndrome. The definition, prevention, and treatment of COVID …

Abstract Novel coronavirus infections 2019 (COVID-19) associated hyperinflammatory
syndromes are well-defined clinical conditions and have a potential risk for severe infection …

Haemophagocytic lymphohistiocytosis (HLH) causing multiorgan failure has been reported
as an acute clinical presentation of COVID-19. However, the literature surrounding HLH in …

Primary and secondary haemophagocytic lymphohistiocytosis (HLH) are hyperferritinaemic
hyperinflammatory syndromes with a common terminal pathway triggered by different …

We read with great interest Dr. Felsenstein review about SARS-CoV2 available treatment
options [1]. It is reasonable to try to stop the ominous cycle established by lymphocytes …

Infection-associated hemophagocytic syndrome (IAHS), a severe complication of various
infections, is potentially fatal. This study aims to determine whether IAHS occurs in critically …