A case of Hemophagocytic lymphohistiocytosis induced by COVID-19, and review of all cases reported in the literature

BU Kayaaslan, D Asilturk, F Eser, M Korkmaz… - The Journal of Infection …, 2021 - jidc.org
Abstract Novel coronavirus infections 2019 (COVID-19) associated hyperinflammatory
syndromes are well-defined clinical conditions and have a potential risk for severe infection …

[HTML][HTML] mTORC inhibitor Sirolimus deprograms monocytes in “cytokine storm” in SARS-CoV2 secondary hemophagocytic lymphohistiocytosis-like syndrome

C Karsulovic, M Lopez, F Tempio… - Clinical Immunology …, 2020 - ncbi.nlm.nih.gov
We read with great interest Dr. Felsenstein review about SARS-CoV2 available treatment
options [1]. It is reasonable to try to stop the ominous cycle established by lymphocytes …

Haemophagocytic syndrome and COVID-19

S Retamozo, P Brito-Zerón, A Sisó-Almirall… - Clinical …, 2021 - Springer
Primary and secondary haemophagocytic lymphohistiocytosis (HLH) are hyperferritinaemic
hyperinflammatory syndromes with a common terminal pathway triggered by different …

Cytokine storm in severe COVID‐19 pneumonia

B Gürsoy, CD Sürmeli, M Alkan, C Satıcı… - Journal of Medical …, 2021 - Wiley Online Library
In this study, laboratorial parameters of hospitalized novel coronavirus (COVID‐19) patients,
who were complicated with severe pneumonia, were compared with the findings of cytokine …

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes
only mild symptoms in the majority of the cases, while immunologic complications such as …

[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …

Emerging trends in COVID-19 treatment: learning from inflammatory conditions associated with cellular therapies

M Cancio, R Ciccocioppo, PRM Rocco, BL Levine… - Cytotherapy, 2020 - Elsevier
Abstract Coronavirus disease 2019 (SARS-CoV2) is an active global health threat for which
treatments are desperately being sought. Even though most people infected experience mild …

Cytokine release syndrome in severe COVID-19

JB Moore, CH June - Science, 2020 - science.org
In December 2019, a new strain of coronavirus, severe acute respiratory syndrome–
coronavirus 2 (SARS-CoV-2), was recognized to have emerged in Wuhan, China. Along …

[HTML][HTML] Secondary hemophagocytic lymphohistiocytosis in post-COVID-19 patients: a report of two cases

P Kalita, D Laishram, B Dey, J Mishra, B Barman… - Cureus, 2021 - ncbi.nlm.nih.gov
Hemophagocytic lymphohistiocytosis (HLH) is a disease that can affect both children and
adults. HLH can be categorized as primary or secondary. Secondary HLH (sHLH) may be …

Case report: a fatal combination of hemophagocytic lymphohistiocytosis with extensive pulmonary microvascular damage in COVID-19 pneumonia

JH von der Thüsen, J van Bommel, JM Kros… - Journal of …, 2021 - Springer
The clinical features of COVID-19 have a considerable range from a mild illness to severe
disease. Underlying pathophysiological mechanisms of the rapidly progressive, and often …