COVID-19-associated cytokine storm syndrome and diagnostic principles: an old and new Issue

X Yongzhi - Emerging microbes & infections, 2021 - Taylor & Francis
ABSTRACT SARS-CoV-2 has claimed 2,137,908 lives in more than a year. Some COVID-19
patients experience sudden and rapid deterioration with the onset of fatal cytokine storm …

Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes

JT England, A Abdulla, CM Biggs, AYY Lee, KA Hay… - Blood Reviews, 2021 - Elsevier
A subset of patients with severe COVID-19 develop profound inflammation and multi-organ
dysfunction consistent with a “Cytokine Storm Syndrome”(CSS). In this review we compare …

Hemophagocytic lymphohistiocytosis: a review inspired by the COVID-19 pandemic

M Soy, P Atagündüz, I Atagündüz, GT Sucak - Rheumatology international, 2021 - Springer
Hemophagocytic syndrome (HPS) or hemophagocytic lymphohistiocytosis (HLH) is an acute
and rapidly progressive systemic inflammatory disorder characterized by cytopenia …

SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients

M Olbei, I Hautefort, D Modos, A Treveil… - Frontiers in …, 2021 - frontiersin.org
Hyper-induction of pro-inflammatory cytokines, also known as a cytokine storm or cytokine
release syndrome (CRS), is one of the key aspects of the currently ongoing SARS-CoV-2 …

[HTML][HTML] Post-COVID-19 syndrome: Insights into a novel post-infectious systemic disorder

M Stoian, B Procopiescu, S Șeitan… - Journal of medicine and …, 2023 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) is currently considered a complex systemic
infectious and inflammatory disease, determined by the infection with severe acute …

COVID-19: consider cytokine storm syndromes and immunosuppression

P Mehta, DF McAuley, M Brown, E Sanchez… - The lancet, 2020 - thelancet.com
As of March 12, 2020, coronavirus disease 2019 (COVID-19) has been con firmed in 125
048 people worldwide, carrying a mortality of approximately 3· 7%, 1 compared with a …

[HTML][HTML] Hyperinflammation with COVID-19: the key to patient deterioration?

K Haigh, ZJ Syrimi, S Irvine, TJ Blanchard… - Clinical Infection in …, 2020 - Elsevier
Background The potential risk of cytokine storm in patients with coronavirus disease 2019
(COVID-19) has been described [1]; we write to share our experience treating a 17-year-old …

Secondary hemophagocytic lymphohistiocytosis, HScore and COVID-19

GG Loscocco - International Journal of Hematology, 2020 - Springer
In a Letter to the Editor published online on May 12 on International Journal of Hematology
[1], Prof Takami exposed, competently, the possibility to treat secondary hemophagocytic …

Clinical criteria for COVID-19-associated hyperinflammatory syndrome: a cohort study

BJ Webb, ID Peltan, P Jensen, D Hoda… - The Lancet …, 2020 - thelancet.com
Background A subset of patients with COVID-19 develops a hyperinflammatory syndrome
that has similarities with other hyperinflammatory disorders. However, clinical criteria …

Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity

L Vanderbeke, P Van Mol, Y Van Herck… - Nature …, 2021 - nature.com
Epidemiological and clinical reports indicate that SARS-CoV-2 virulence hinges upon the
triggering of an aberrant host immune response, more so than on direct virus-induced …