İ Aktaş, İ Armağan - Adıyaman Üniversitesi Sağlık Bilimleri Dergisi, 2019 - dergipark.org.tr
Purpose: In this study, we evaluated the potential hepatoprotective effects of silymarin on valproic acid-induced liver injury by histological and biochemical parameters in rat liver …
Silymarin is a complex of five major compounds, and silibinin is the most biologically active component of the complex. The aim of this study was to investigate, evaluate and confirm the …
BM Razavi, G Karimi - Iranian journal of basic medical sciences, 2016 - ncbi.nlm.nih.gov
Cardiac disorders remain one of the most important causes of death in the world. Oxidative stress has been suggested as one of the molecular mechanisms involved in drug-induced …
Doxorubicin (DOX) is the most effective and frequently used anticancer drug. This work aimed to study the protective role of silymarin (SIL) against DOX induced cardiotoxicity. Forty …
In this study, the effects of lacidipine (LAC), ramipril (RAM), and valsartan (VAL) on biochemical and histopathologic changes in heart tissue were studied in rats with …
İ Aktaş, D Bayram - Harran Üniversitesi Veteriner Fakültesi Dergisi, 2020 - dergipark.org.tr
In this study; we aimed to investigate the protective effects of silymarin (SLY) against kidney damage on valproic acid (VPA)-induced rats using histological and biochemical evaluations …
Background: despite its vast utility in clinical oncology, the use of doxorubicin is limited by a potentially fatal cardiomyopathy and congestive heart failure. Free radical formation and …
NS Toutounchi, A Afrooziyan… - Pharmaceutical …, 2017 - library.go4manusub.com
Background: Rosmarinic acid is a polyphenolic compound with considerable antioxidant activities. We aimed to investigate its cardioprotective effects against isoproterenol-induced …
Silymarin, derived from Silybum marianum, has been used in traditional medicine for various ailments. In this study, the cardioprotective and hepatoprotective effects of silymarin against …