The treatment effect of silymarin on heart damage in rats

I Aktas, M Ozgocmen - 2020 - annalsmedres.org
Aim: In this article, we evaluated the possible cardiac protective effects of silymarin on
valproic acid-induced heart injury by histological and biochemical parameters in rat heart …

Investigation of the positive effects of silymarin on valproic acid-induced liver damage in rats

İ Aktaş, İ Armağan - Adıyaman Üniversitesi Sağlık Bilimleri Dergisi, 2019 - dergipark.org.tr
Purpose: In this study, we evaluated the potential hepatoprotective effects of silymarin on
valproic acid-induced liver injury by histological and biochemical parameters in rat liver …

The protective effects of silymarin against doxorubicin-induced cardiotoxicity and hepatotoxicity in rats

A Rašković, N Stilinović, J Kolarović, V Vasović… - Molecules, 2011 - mdpi.com
Silymarin is a complex of five major compounds, and silibinin is the most biologically active
component of the complex. The aim of this study was to investigate, evaluate and confirm the …

[HTML][HTML] Protective effect of silymarin against chemical-induced cardiotoxicity

BM Razavi, G Karimi - Iranian journal of basic medical sciences, 2016 - ncbi.nlm.nih.gov
Cardiac disorders remain one of the most important causes of death in the world. Oxidative
stress has been suggested as one of the molecular mechanisms involved in drug-induced …

[PDF][PDF] Silymarin decreases the expression of VEGF-A, iNOS and caspase-3 and preserves the ultrastructure of cardiac cells in doxorubicin induced cardiotoxicity in …

GM Attia, RA Elmansy, SA Algaidi - Int J Clin Exp Med, 2017 - e-century.us
Doxorubicin (DOX) is the most effective and frequently used anticancer drug. This work
aimed to study the protective role of silymarin (SIL) against DOX induced cardiotoxicity. Forty …

Comparing effects of lacidipine, ramipril, and valsartan against experimentally induced myocardial infarcted rats

Y Bayir, Z Halici, E Karakus, A Albayrak, I Ferah… - Cardiovascular …, 2012 - Springer
In this study, the effects of lacidipine (LAC), ramipril (RAM), and valsartan (VAL) on
biochemical and histopathologic changes in heart tissue were studied in rats with …

Investigation of the effects of silymarin on valproic acid-induced kidney damage in rats

İ Aktaş, D Bayram - Harran Üniversitesi Veteriner Fakültesi Dergisi, 2020 - dergipark.org.tr
In this study; we aimed to investigate the protective effects of silymarin (SLY) against kidney
damage on valproic acid (VPA)-induced rats using histological and biochemical evaluations …

Doxorubicin-induced cardiotoxicity in mice; protection by silymarin

HA Aniss, C AdLy, AEM Said… - The Egyptian Journal of …, 2012 - journals.ekb.eg
Background: despite its vast utility in clinical oncology, the use of doxorubicin is limited by a
potentially fatal cardiomyopathy and congestive heart failure. Free radical formation and …

Cardioprotective effects of rosmarinic acid on isoproterenol-induced myocardial infarction in rats

NS Toutounchi, A Afrooziyan… - Pharmaceutical …, 2017 - library.go4manusub.com
Background: Rosmarinic acid is a polyphenolic compound with considerable antioxidant
activities. We aimed to investigate its cardioprotective effects against isoproterenol-induced …

Cardioprotective and Hepatoprotective Potential of Silymarin in Paracetamol-Induced Oxidative Stress

B Okiljević, N Martić, S Govedarica, B Andrejić Višnjić… - Pharmaceutics, 2024 - mdpi.com
Silymarin, derived from Silybum marianum, has been used in traditional medicine for various
ailments. In this study, the cardioprotective and hepatoprotective effects of silymarin against …