In younger adults, arousal amplifies attentional focus to the most salient or goal-relevant
information while suppressing other information. A computational model of how the locus …

The arousal-biased competition model predicts that arousal increases the gain on neural
competition between stimuli representations. Thus, the model predicts that arousal …

Selectively attending to relevant information while blocking out distractors is crucial for goal-
directed behavior, yet with advancing age, deficits emerge in attentional selectivity …

Recent models posit that bursts of locus ceruleus (LC) activity amplify neural gain such that
limited attention and encoding resources focus even more on prioritized mental …

The locus coeruleus (LC) regulates attention via the release of norepinephrine (NE), with
levels of tonic LC activity constraining the intensity of phasic LC responses. In the current …

Mood, motivation, attention, and arousal are behavioral states having a profound impact on
cognition. Behavioral states are mediated though the peripheral nervous system and …

Previously it has been theorized that differential functioning of the locus coeruleus–
norepinephrine (LC–NE) system affects people's ability to regulate arousal, which has …

Arousal plays a central role in a wide variety of phenomena, including wakefulness,
autonomic function, affect and emotion. Despite its importance, it remains unclear as to how …

Cognitive control lies at the core of human adaptive behaviour. Humans vary substantially in
their ability to execute cognitive control with respect to optimally facing environmental …

Experimental evidence has implicated multiple neurotransmitter systems in either the direct
or indirect modulation of cortical arousal and attention circuitry. In this review, we selectively …