Inflammation, frailty and cardiovascular disease

P Soysal, F Arik, L Smith, SE Jackson… - Frailty and cardiovascular …, 2020 - Springer
Chronic inflammation, which is called “inflamm-aging”, is characterized by an increased
level of inflammatory cytokines in response to physiological and environmental stressors …

Drivers of age‐related inflammation and strategies for healthspan extension

EL Goldberg, VD Dixit - Immunological reviews, 2015 - Wiley Online Library
Aging is the greatest risk factor for the development of chronic diseases such as arthritis,
type 2 diabetes, cardiovascular disease, kidney disease, Alzheimer's disease, macular …

Aging, inflammation and the environment

A Bektas, SH Schurman, R Sen, L Ferrucci - Experimental gerontology, 2018 - Elsevier
The aging process is driven by interrelated mechanisms that lead to the emergence of
characteristic phenotypes that include changes in body composition, energy production and …

[HTML][HTML] Inflammation-accelerated senescence and the cardiovascular system: mechanisms and perspectives

R Del Pinto, C Ferri - International journal of molecular sciences, 2018 - mdpi.com
Low-grade chronic inflammation is a common denominator in atherogenesis and related
diseases. Solid evidence supports the occurrence of an impairment in the innate and …

[HTML][HTML] The effect of ageing on the resolution of inflammation

W Sendama - Ageing Research Reviews, 2020 - Elsevier
Ageing is associated with the development of a low-level, systemic, chronic inflammation
known as “inflammaging”. This chronic inflammatory state can contribute to diseases of …

Molecular mechanisms of aging-associated inflammation

D Sarkar, PB Fisher - Cancer letters, 2006 - Elsevier
A direct relationship exists between aging and increasing incidences of chronic diseases. In
fact, with most age-associated diseases individuals manifest an underlying chronic …

[HTML][HTML] Ageing: from inflammation to cancer

GC Leonardi, G Accardi, R Monastero, F Nicoletti… - Immunity & …, 2018 - Springer
Ageing is the major risk factor for cancer development. Hallmark of the ageing process is
represented by inflammaging, which is a chronic and systemic low-grade inflammatory …

Regulation of inflammation as an anti‐aging intervention

J Neves, P Sousa‐Victor - The FEBS journal, 2020 - Wiley Online Library
Aging is accompanied by a decline in physiological integrity and a loss of regenerative
capacity in many tissues. The development of interventions that prevent or reverse age …

[HTML][HTML] Increased immunosuppression impairs tissue homeostasis with aging and age-related diseases

A Salminen - Journal of molecular medicine, 2021 - Springer
Chronic low-grade inflammation is a common hallmark of the aging process and many age-
related diseases. There is substantial evidence that persistent inflammation is associated …

Inflammaging as a major characteristic of old people: can it be prevented or cured?

C Franceschi - Nutrition reviews, 2007 - academic.oup.com
Widespread aging at the population level is a recent phenomenon that emerged in affluent
societies. Inflammation is necessary to cope with damaging agents and is crucial for …