Low SOX17 expression is a prognostic factor and drives transcriptional dysregulation and esophageal cancer progression

IY Kuo, CC Wu, JM Chang, YL Huang… - … journal of cancer, 2014 - Wiley Online Library
The transcriptional network of the SRY (sex determining region Y)‐box 17 (SOX17) and the
prognostic impact of SOX17 protein expression in human cancers remain largely unclear. In …

[HTML][HTML] Upregulation of sex-determining region Y-box 9 (SOX9) promotes cell proliferation and tumorigenicity in esophageal squamous cell carcinoma

Y Hong, W Chen, X Du, H Ning, H Chen, R Shi, S Lin… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Sex-determining region Y-box 9 (SOX9), a vital transcription factor, play important roles in
numerous biological and pathological processes. However, the clinical significance and …

Expression and clinical relevance of SOX9 in gastric cancer

P Mesquita, AF Freire, N Lopes, R Gomes… - Disease …, 2019 - Wiley Online Library
Gastric cancer is one of the most frequent tumours and the third leading cause of cancer‐
related death worldwide. The investigation of new biomarkers that can predict patient …

[HTML][HTML] Knockdown of SOX12 expression inhibits the proliferation and metastasis of lung cancer cells

L Wang, F Hu, S Shen, H Xiao, G Li… - American Journal of …, 2017 - ncbi.nlm.nih.gov
Sex determining region Y-box protein 12 (SOX12) plays an important role in the
tumorigenesis of hepatocellular carcinoma. The involvement of SOX12 in human lung …

SOX9/miR-203a axis drives PI3K/AKT signaling to promote esophageal cancer progression

L Wang, Z Zhang, X Yu, Q Li, Q Wang, A Chang… - Cancer letters, 2020 - Elsevier
Deregulation of SOX9 in esophageal cancer has been reported. However, the regulatory
mechanisms underlying SOX9 during esophageal squamous cell carcinoma (ESCC) …

Expression features of SOX9 associate with tumor progression and poor prognosis of hepatocellular carcinoma

X Guo, L Xiong, T Sun, R Peng, L Zou, H Zhu… - Diagnostic …, 2012 - Springer
Background SOX9 as a member of the SOX (SRY [sex determining region Y] box) gene
superfamily has been previously demonstrated to be a proto-oncogene in a variety of …

Characterization of Tumor-Suppressive Function of SOX6 in Human Esophageal Squamous Cell Carcinoma

YR Qin, H Tang, F Xie, H Liu, Y Zhu, J Ai, L Chen… - Clinical cancer …, 2011 - AACR
Purpose: By using cDNA microarray analysis, we identified a transcriptional factor, SOX6,
was frequently downregulated in esophageal squamous cell carcinoma (ESCC). The aim of …

[HTML][HTML] Knockdown of SOX18 inhibits the proliferation, migration and invasion of hepatocellular carcinoma cells

G Wang, Z Wei, H Jia, W Zhao… - Oncology …, 2015 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is one of the most common malignancies in the world.
Recent studies have demonstrated that SOX18 is highly expressed in various types of …

Upregulation of SOX9 promotes cell proliferation, migration and invasion in lung adenocarcinoma

X Wang, Y Ju, MI Zhou, X Liu… - Oncology …, 2015 - spandidos-publications.com
Sex determining region Y‑box 9 (SOX9) is an important transcription factor in development
and has been implicated in several types of cancer. Although the association between …

Sox17 regulates proliferation and cell cycle during gastric cancer progression

YW Ye, JH Wu, CM Wang, Y Zhou, CY Du, BQ Zheng… - Cancer letters, 2011 - Elsevier
Sox17, a transcription factor, was considered as an antagonist to inhibit canonical Wnt/β-
catenin signaling in several malignant tumors. Extremely little is known about Sox17 in …