High levels of SOX4 expression have been found in a variety of human cancers, such as
lung, brain and breast cancers. However, the expression of SOX4 in gastric tissues remains …

We report the emerging role of microRNA (miRNA) deregulation associated with activation
of an oncogene SOX4 (a member of the SRY-related HMG-box) in esophageal carcinoma …

Background SRY (sex-determining region Y)-box 2 (SOX2) is a crucial transcription factor for
the maintenance of embryonic stem cell pluripotency and the determination of cell fate …

Purpose: By using cDNA microarray analysis, we identified a transcriptional factor, SOX6,
was frequently downregulated in esophageal squamous cell carcinoma (ESCC). The aim of …

We previously showed that high expression levels of SOX9 correlate with hepatocellular
carcinoma (HCC) progression. However, the exact role that SOX9 plays in HCC remains …

Sex determining region Y‑box 9 (SOX9) is an important transcription factor in development
and has been implicated in several types of cancer. Although the association between …

SOX9 belongs to the SOX (Sry-related high-mobility group box) family and acts as a
transcription factor that plays a central role in the development and differentiation of multiple …

SOX transcription factors are critical regulators of development, homeostasis and disease
progression and their dysregulation is a common finding in various cancers. SOX9 belongs …

Background High levels of SOX2 protein are correlated with increased dissemination of
breast cancer. However, the underlying molecular mechanisms are not fully understood …

Sex determining region Y‑box protein 5 (SOX5) is a transcriptional factor and serves
important roles in various cancer types; however, the pathological role of SOX5 in patients …