[HTML][HTML] Preparation, optimization, and characterization of chitosan-coated solid lipid nanoparticles for ocular drug delivery

F Wang, M Zhang, D Zhang, Y Huang… - Journal of Biomedical …, 2018 - ncbi.nlm.nih.gov
The present study aimed to develop and optimize chitosan coated solid lipid nanoparticles
(chitosan-SLNs) encapsulated with methazolamide. Chitosan-SLNs were successfully …

Methazolamide-loaded solid lipid nanoparticles modified with low-molecular weight chitosan for the treatment of glaucoma: vitro and vivo study

F Wang, L Chen, D Zhang, S Jiang, K Shi… - Journal of drug …, 2014 - Taylor & Francis
The aims of this study were to design and characterize methazolamide (MTZ)-loaded solid
lipid nanoparticles (SLN) with and without modification of low molecular weight chitosan …

Optimization of methazolamide-loaded solid lipid nanoparticles for ophthalmic delivery using Box–Behnken design

F Wang, L Chen, S Jiang, J He, X Zhang… - Journal of liposome …, 2014 - Taylor & Francis
The purpose of the present study was to optimize methazolamide (MTZ)-loaded solid lipid
nanoparticles (SLNs) which were used as topical eye drops by evaluating the relationship …

Nanostructured lipid carrier (NLC) coated with Chitosan Oligosaccharides and its potential use in ocular drug delivery system

Q Luo, J Zhao, X Zhang, W Pan - International journal of pharmaceutics, 2011 - Elsevier
The objective of the present investigation was to explore the potential of the Chitosan
Oligosaccharides (COS)-coated NLC (nanostructured lipid carrier) for ocular drug delivery …

Development and characterization of itraconazole-loaded solid lipid nanoparticles for ocular delivery

B Mohanty, DK Majumdar, SK Mishra… - Pharmaceutical …, 2015 - Taylor & Francis
The purpose of this study was to investigate the feasibility of entrapping water-insoluble drug
itraconazole into solid lipid nanoparticles (SLNs) for topical ocular delivery. The drug-loaded …

Chitosan-coupled solid lipid nanoparticles: tuning nanostructure and mucoadhesion

G Sandri, S Motta, MC Bonferoni, P Brocca… - European Journal of …, 2017 - Elsevier
Abstract Solid Lipid Nanoparticles (SLNs) composed of biodegradable physiological lipids
have been widely proposed as efficient drug delivery systems, also for ophthalmic …

Design of cationic lipid nanoparticles for ocular delivery: Development, characterization and cytotoxicity

JF Fangueiro, T Andreani, MA Egea, ML Garcia… - International journal of …, 2014 - Elsevier
In the present study we have developed lipid nanoparticle (LN) dispersions based on a
multiple emulsion technique for encapsulation of hydrophilic drugs or/and proteins by a full …

[HTML][HTML] Development and optimization of solid lipid nanoparticles coated with chitosan and poly (2-ethyl-2-oxazoline) for ocular drug delivery of ciprofloxacin

AL Onugwu, AA Attama, PO Nnamani… - Journal of Drug Delivery …, 2022 - Elsevier
Many formulation strategies have been employed to improve ocular bioavailability of topical
eye drops. The aim of this study was to develop and evaluate a series of solid lipid …

Chitosan coated sodium alginate–chitosan nanoparticles loaded with 5-FU for ocular delivery: In vitro characterization and in vivo study in rabbit eye

RC Nagarwal, R Kumar, JK Pandit - European Journal of Pharmaceutical …, 2012 - Elsevier
The objective of the study was to develop chitosan (CH) coated sodium alginate–chitosan
(SA–CH) nanoparticles, ie CH-SA–CH NPs loaded with 5-FU for ophthalmic delivery. Drug …

Development of timolol-loaded galactosylated chitosan nanoparticles and evaluation of their potential for ocular drug delivery

R Zhao, J Li, J Wang, Z Yin, Y Zhu, W Liu - AAPS PharmSciTech, 2017 - Springer
This study was conducted to develop timolol maleate (TM)-loaded galactosylated chitosan
(GC) nanoparticles (NPs)(TM-GC-NPs) followed by optimization via a four-level and three …