High‐throughput (HT) screening drug discovery, during which thousands or millions of
compounds are screened, remains the key methodology for identifying active chemical …

Enormous advances in our understanding of the chemistry underlying life processes have
identified new targets for therapeutic agents. The discovery of effective therapeutics to …

Recent advances in the biological and analytical sciences have led to unprecedented
interest in the discoveryand quantitation of endogenous molecules that serve as indicators …

This review highlights the many roles mass spectrometry plays in the discovery and
development of new therapeutics by both the pharmaceutical and the biotechnology …

High-resolution mass spectrometry will dramatically change our drug-discovery bioanalysis
procedures | Bioanalysis Future Science Logo Search This Journal Anywhere Quick Search in …

Drugs are launched to market after the lengthy process of development. Despite careful
preclinical assessment, there is still a significant risk that a drug candidate may elicit adverse …

The role of mass spectrometry (MS) has become more important in most application
domains in recent years. Pharmaceutical analysis is specific due to its stringent regulation …

High throughput screening (HTS) of molecular analytes is in high demand from and
implemented in many areas of chemistry, medicine and industrial biotechnology including …

Mass spectrometry has suddenly expanded out of research and assay laboratories into
biology, medicine and therapeutics. Electrospray ionization and matrix-assisted laser …

The first edition of this now classic work helped to establish mass spectrometry as the
premier tool for drug metabolism studies. Completely rewritten from start to finish, Using …