The capacity of antibodies to engage with immune cells via the Fc region is important in
preventing and controlling many infectious diseases. The evolution of such antibodies …

Neutralizing antibodies are known to have a crucial role in protecting against SARS-CoV-2
infection and have been suggested to be a useful correlate of protection for vaccine clinical …

A growing body of evidence shows that fragment crystallizable (Fc)-dependent antibody
effector functions play an important role in protection from severe acute respiratory …

SARS-CoV-2 has caused the global COVID-19 pandemic. Although passively delivered
neutralizing antibodies against SARS-CoV-2 show promise in clinical trials, their mechanism …

Antibody-dependent cellular cytotoxicity (ADCC) responses to viral infection are a form of
antibody regulated immune responses mediated through the Fc fragment. Whether severe …

Beyond neutralization, antibodies binding to their Fc receptors elicit several innate immune
functions including antibody-dependent complement deposition (ADCD), antibody …

Antibody-dependent enhancement (ADE) of infection is generally known for many viruses. A
potential risk of ADE in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Major advances have been made in understanding the dynamics of humoral immunity
briefly after the acute coronavirus disease 2019 (COVID-19). However, knowledge …

ABSTRACT The coronavirus disease 2019 (COVID-19) pandemic has raised concerns
about the detrimental effects of antibodies. Antibody-dependent enhancement (ADE) of …

Long-term antibody responses and neutralizing activities in response to SARS-CoV-2
infection are not yet clear. Here we quantify immunoglobulin M (IgM) and G (IgG) antibodies …