Comparing the cytokine storms of COVID-19 and pandemic influenza

LM Pacheco-Hernández… - Journal of interferon & …, 2022 - liebertpub.com
Emerging respiratory viruses are major health threats due to their potential to cause massive
outbreaks. Over the past 2 years, the coronavirus disease 2019 (COVID-19) pandemic has …

Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm

PA Mudd, JC Crawford, JS Turner, A Souquette… - Science …, 2020 - science.org
We pursued a study of immune responses in coronavirus disease 2019 (COVID-19) and
influenza patients. Compared to patients with influenza, patients with COVID-19 exhibited …

[HTML][HTML] Establishing a unified COVID-19 “immunome”: integrating coronavirus pathogenesis and host immunopathology

E Wauters, K Thevissen, C Wouters… - Frontiers in …, 2020 - frontiersin.org
Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), has created an unprecedented global health crisis. Because …

Differential cytokine signatures of SARS-CoV-2 and influenza infection highlight key differences in pathobiology

AH Karaba, W Zhou, LL Hsieh, A Figueroa… - MedRxiv, 2021 - medrxiv.org
Background Several inflammatory cytokines are upregulated in severe COVID-19. We
compared cytokines in COVID-19 versus influenza in order to define differentiating features …

[HTML][HTML] Mechanistic insights into the immune pathophysiology of COVID-19; an in-depth review

A Shafqat, S Shafqat, SA Salameh, J Kashir… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …

[HTML][HTML] Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in
the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; …

[HTML][HTML] The trinity of COVID-19: immunity, inflammation and intervention

MZ Tay, CM Poh, L Rénia, PA MacAry… - Nature Reviews …, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …

Immune characterization and profiles of SARS-CoV-2 infected patients reveals potential host therapeutic targets and SARS-CoV-2 oncogenesis mechanism

M Policard, S Jain, S Rego, S Dakshanamurthy - Virus Research, 2021 - Elsevier
The spread of SARS-CoV-2 and the increasing mortality rates of COVID-19 create an urgent
need for treatments, which are currently lacking. Although vaccines have been approved by …

[HTML][HTML] The COVID-19 cytokine storm; what we know so far

D Ragab, H Salah Eldin, M Taeimah… - Frontiers in …, 2020 - frontiersin.org
COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the
WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract …