Fibrinogen is essential for aggregating platelets with adenosine diphosphate (ADP) and was
recently shown to bind to platelets stimulated with ADP. The present work confirms the …

A pentadecapeptide, derived from a staphylococcal protease digest of the 27-residue
carboxy-terminal cyanogen bromide fragment of human fibrinogen γ chain, inhibits binding …

Optimal conditions for a method to simultaneously measure aggregation in 96 samples
using a microplate reader were developed. The temperature of the assay was set at 25° C …

Fibrinogen binding to platelet plasma membranes, which is a prerequisite for platelet
aggregation, was determined by incubating 125I-labeled fibrinogen with isolated …

The interaction of fibrinogen with membrane glycoprotein GPIIb-IIIa regulates platelet
aggregation. This ligand: integrin receptor interaction elicits conformational changes in …

The platelet-binding characteristics of three different antibodies that completely block
adenosine diphosphate (ADP)-induced platelet fibrinogen binding and react with …

Familial hypercholesterolemia (FH) is a disease marked by a high incidence of thrombotic
episodes and hypersensitivity of the patients' platelets to naturally occurring aggregating …

We report that the 27-residue carboxy-terminal cyanogen bromide fragment of human
fibrinogen γ chain inhibits binding of [125 I] fibrinogen to human platelet receptors and …

The role of fibrinogen as a cofactor in platelet aggregation is mediated by its binding to
platelet receptors that are induced by stimuli such as ADP. In the present study, we …

Fibronectin binds to specific receptors on the surface of washed, thrombin-activated
platelets. Evidence suggests that these receptors are closely associated with the platelet …