[HTML][HTML] Modulation of platelet function through adhesion receptors. A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and …
B Savage, SJ Shattil, ZM Ruggeri - Journal of Biological Chemistry, 1992 - Elsevier
We have found that the form of glycoprotein (GP) IIb-IIIa (integrin alpha IIb beta 3) expressed
on nonstimulated platelets is a functional receptor that mediates selective and irreversible …
on nonstimulated platelets is a functional receptor that mediates selective and irreversible …
[HTML][HTML] Related binding mechanisms for fibrinogen, fibronectin, von Willebrand factor, and thrombospondin on thrombin-stimulated human platelets
EF Plow, RP McEver, BS Coller, VL Woods Jr… - Blood, 1985 - Elsevier
Fibrinogen, fibronectin, von Willebrand factor, and thrombospondin are four large
glycoproteins that bind to thrombin-stimulated platelets and influence cellular adhesive …
glycoproteins that bind to thrombin-stimulated platelets and influence cellular adhesive …
[HTML][HTML] Adhesion of platelets to surface-bound fibrinogen under flow
TN Zaidi, LV McIntire, DH Farrell, P Thiagarajan - Blood, 1996 - Elsevier
After platelet activation, fibrinogen mediates platelet-platelet interactions leading to platelet
aggregation. In addition, fibrinogen can also function as a cell adhesion molecule, providing …
aggregation. In addition, fibrinogen can also function as a cell adhesion molecule, providing …
[HTML][HTML] Resting platelets contain a substantial centrally located pool of glycoprotein IIb-IIIa complex which may be accessible to some but not other extracellular …
VL Woods Jr, LE Wolff, DM Keller - Journal of Biological Chemistry, 1986 - Elsevier
Recent evidence suggests the presence in resting platelets of centrally located
compartments of glycoprotein (GP) IIb-IIIa. We have employed an experimental procedure …
compartments of glycoprotein (GP) IIb-IIIa. We have employed an experimental procedure …
Collagen-platelet interactions: evidence for a direct interaction of collagen with platelet GPIa/IIa and an indirect interaction with platelet GPIIb/IIIa mediated by adhesive …
BS Coller, JH Beer, LE Scudder, MH Steinberg - 1989 - ashpublications.org
Using intact human platelets as the immunogen and a functional, collagen-coated bead
agglutination assay, we have produced a murine monoclonal antibody (6F1) that blocks the …
agglutination assay, we have produced a murine monoclonal antibody (6F1) that blocks the …
The effect of peptides and monoclonal antibodies that bind to platelet glycoprotein IIb-IIIa complex on the development of clot tension
I Cohen, DL Burk, JG White - 1989 - ashpublications.org
The development of tension in platelet-rich clots is a manifestation of fibrin polymer binding
to platelets as well as platelet contractile activity. Arg-Gly-Asp (RGD)-containing peptides of …
to platelets as well as platelet contractile activity. Arg-Gly-Asp (RGD)-containing peptides of …
Further studies on the topography of the N-terminal region of human platelet glycoprotein IIIa. Localization of monoclonal antibody epitopes and the putative …
JJ Calvete, J Arias, MV Alvarez, MM Lopez… - Biochemical …, 1991 - portlandpress.com
The precise localization of the epitopes for six monoclonal antibodies specific for the N-
terminal region of human platelet glycoprotein IIIa (GPIIIa) was determined. The epitope for …
terminal region of human platelet glycoprotein IIIa (GPIIIa) was determined. The epitope for …
[PDF][PDF] The platelet membrane glycoprotein IIb-IIIa complex
DR Phillips, IF Charo, LV Parise, LA Fitzgerald - 1988 - researchgate.net
By David R. Phillips, Israel F. Charo, Leslie V. Parise, and Laurence A. Fitzgerald A NEW
FAMILY of cell-surface receptors has been identified that mediates a wide variety of cell-cell …
FAMILY of cell-surface receptors has been identified that mediates a wide variety of cell-cell …
[HTML][HTML] A conformation-dependent epitope of human platelet glycoprotein IIIa
WC Kouns, CD Wall, MM White, CF Fox… - Journal of Biological …, 1990 - Elsevier
This study explores conformational states of human platelet glycoprotein IIIa (GP IIIa) and
possible mechanisms of fibrinogen receptor exposure. D3GP3 is an IgG1, kappa …
possible mechanisms of fibrinogen receptor exposure. D3GP3 is an IgG1, kappa …
Thrombin-induced platelet membrane glycoprotein IIb and IIIa complex formation. An electron microscope study.
MJ Polley, LL Leung, FY Clark… - The Journal of …, 1981 - rupress.org
The topographic relationships of platelet membrane glycoprotein IIb and glycoprotein IIIa
have been studied in stimulated and unstimulated human platelets using immunoelectron …
have been studied in stimulated and unstimulated human platelets using immunoelectron …