Evaluation of a new artificial tear formulation for the management of tear film stability and visual function in patients with dry eye

G Torkildsen, M Brujic, MS Cooper… - Clinical …, 2017 - Taylor & Francis
Purpose Artificial tears are the first line of therapy for dry eye disease (DED) and are also the
most frequently used treatment approach for this common condition. Despite this, there are …

Efficacy and safety of two new formulations of artificial tears in subjects with dry eye disease: a 3-month, multicenter, active-controlled, randomized trial

PA Simmons, H Liu, C Carlisle-Wilcox… - Clinical …, 2015 - Taylor & Francis
Purpose To evaluate and compare the efficacy and safety of two investigational artificial tear
formulations (CHO-1 and CHO-2) containing carmellose sodium, hyaluronic acid at different …

Extending the duration of tear film protection in dry eye syndrome: review and retrospective case series study of the hydroxypropyl cellulose ophthalmic insert

AH Wander, BH Koffler - The ocular surface, 2009 - Elsevier
Abstract options for extending the duration of tear film protection in dry eyes include artificial
tear formulations with enhanced viscosity/polymeric systems, ocular ointments and gels …

[HTML][HTML] Personalized management of dry eye disease: beyond artificial tears

C Matossian, M Crowley, L Periman… - Clinical Ophthalmology …, 2022 - ncbi.nlm.nih.gov
Dry eye disease (DED) is a multifactorial disease of the ocular surface that may be
accompanied by discomfort and visual disturbances to a level that reduces quality of life …

Clinical outcomes of fixed versus as-needed use of artificial tears in dry eye disease: a 6-week, observer-masked phase 4 clinical trial

P Asbell, AJ Vingrys, J Tan, A Ogundele… - … & Visual Science, 2018 - iovs.arvojournals.org
Purpose: To evaluate the clinical effects of using fixed (four times daily [QID]) versus as-
needed (PRN) dosing of an artificial tear product (polyethylene glycol/propylene glycol …

[HTML][HTML] Efficacy, safety, and acceptability of a lipid-based artificial tear formulation: a randomized, controlled, multicenter clinical trial

PA Simmons, C Carlisle-Wilcox, R Chen, H Liu… - Clinical …, 2015 - Elsevier
Purpose Dry eye disease is highly prevalent worldwide, causing discomfort and visual
disturbances that can limit basic activities such as reading and driving. Although artificial …

Tear film stabilization and symptom improvement in dry eye disease: The role of hyaluronic acid and trehalose eyedrops versus carmellose sodium

JM Sánchez-González, C Silva-Viguera… - Journal of Clinical …, 2023 - mdpi.com
This study evaluated the effectiveness of hyaluronic acid and trehalose (HA/trehalose)
eyedrops in managing dry eye disease (DED) symptoms by measuring tear stability and …

Developing evidence-based guidance for the treatment of dry eye disease with artificial tear supplements: A six-month multicentre, double-masked randomised …

JP Craig, A Muntz, MTM Wang, D Luensmann, J Tan… - The ocular …, 2021 - Elsevier
Purpose To assess the six-month therapeutic profiles of lipid and non-lipid-based artificial
tear supplements in managing dry eye disease (DED). Methods Ninety-nine participants …

Artificial tear formulations

FJ HOLLY - International Ophthalmology Clinics, 1980 - journals.lww.com
Diminution in the quantity of tears or decreased stability of the tear film, or both, result in a
dry eye. Dry eye states decrease visual acuity, cause mild to intense discomfort, and …

[PDF][PDF] Dry eye disease treatment: the role of tear substitutes, their future, and an updated classification.

S Barabino, JM Benitez-Del-Castillo… - European Review for …, 2020 - europeanreview.org
OBJECTIVE: The aim of this review is to summarize the results of a consensus meeting held
by a group of experts in dry eye disease (DED) to discuss the importance of tear substitutes …