Sources of information waste in neuroimaging: mishandling structures, thinking dichotomously, and over-reducing data

G Chen, PA Taylor, J Stoddard, RW Cox, PA Bandettini… - BioRxiv, 2021 - biorxiv.org
Neuroimaging relies on separate statistical inferences at tens of thousands of spatial
locations. Such massively univariate analysis typically requires an adjustment for multiple …

[HTML][HTML] Fighting or embracing multiplicity in neuroimaging? neighborhood leverage versus global calibration

G Chen, PA Taylor, RW Cox, L Pessoa - NeuroImage, 2020 - Elsevier
Neuroimaging faces the daunting challenge of multiple testing–an instance of multiplicity–
that is associated with two other issues to some extent: low inference efficiency and poor …

Removal of scanner effects in covariance improves multivariate pattern analysis in neuroimaging data

AA Chen, JC Beer, NJ Tustison, PA Cook… - BioRxiv, 2019 - biorxiv.org
To acquire larger samples for answering complex questions in neuroscience, researchers
have increasingly turned to multi-site neuroimaging studies. However, these studies are …

Highlight Results, Don't Hide Them: enhance interpretation, reduce biases and improve reproducibility

PA Taylor, RC Reynolds, V Calhoun… - Neuroimage, 2023 - Elsevier
Most neuroimaging studies display results that represent only a tiny fraction of the collected
data. While it is conventional to present" only the significant results" to the reader, here we …

Mitigating site effects in covariance for machine learning in neuroimaging data

AA Chen, JC Beer, NJ Tustison, PA Cook… - Human brain …, 2022 - Wiley Online Library
To acquire larger samples for answering complex questions in neuroscience, researchers
have increasingly turned to multi‐site neuroimaging studies. However, these studies are …

Analytical transparency and reproducibility in human neuroimaging studies

M Picciotto - Journal of Neuroscience, 2018 - Soc Neuroscience
The Journal of Neuroscience is committed to editorial transparency and scientific
excellence. Consistent with these goals, this editorial is the first of a series aimed at …

Site effects how-to and when: An overview of retrospective techniques to accommodate site effects in multi-site neuroimaging analyses

JMM Bayer, PM Thompson, CRK Ching, M Liu… - Frontiers in …, 2022 - frontiersin.org
Site differences, or systematic differences in feature distributions across multiple data-
acquisition sites, are a known source of heterogeneity that may adversely affect large-scale …

Handling multiplicity in neuroimaging through Bayesian lenses with multilevel modeling

G Chen, Y Xiao, PA Taylor, JK Rajendra, T Riggins… - Neuroinformatics, 2019 - Springer
Here we address the current issues of inefficiency and over-penalization in the massively
univariate approach followed by the correction for multiple testing, and propose a more …

Overfitting the literature to one set of stimuli and data

T Grootswagers, AK Robinson - Frontiers in human neuroscience, 2021 - frontiersin.org
A large number of papers in Computational Cognitive Neuroscience are developing and
testing novel analysis methods using one specific neuroimaging dataset and problematic …

Moving beyond processing and analysis-related variation in neuroscience

X Li, NB Esper, L Ai, S Giavasis, H Jin, E Feczko, T Xu… - BioRxiv, 2021 - biorxiv.org
When fields lack consensus standards and ground truths for their analytic methods,
reproducibility can be more of an ideal than a reality. Such has been the case for functional …