Purpose Apelin is an adipokine that plays a role in the regulation of many biological
functions in mammals including the neuroendocrine, cardiovascular, immune systems …

Apelin and its receptor (APJ) are involved in the regulation of a variety of pathophysiological
processes. We studied the effect of apelin treatment on obesity-induced type 2 diabetes …

Apelin is an adipocyte-derived peptide that plays an important role in regulation of energy
homoeostasis and decrease of insulin resistance. We investigated the effects of exercise …

Type 2 diabetes mellitus is a common type of diabetes and considered as multifactorial
disease. Apelin is an adipokine which secreted from white adipose tissue and involved in …

Apelin, a new identified adipokine, and its G protein–coupled receptor named APJ are
widely expressed in various tissues. Apelin has been found to play important roles in the …

Introduction: Type 2 diabetes mellitus (T2DM) is a chronic disorder characterized by
persistent hyperglycemia. Chronic hyperglycemia in diabetes mellitus can cause …

Apelin, an adipocyte-secreted factor upregulated by insulin, is increased in adipose tissue
(AT) and plasma with obesity. Apelin was recently identified as a new player in the control of …

Background: The physiological role of apelin, an adipokine secreted by adipose tissue, in
insulin resistance and type 2 diabetes has been identified. The aim of this study was to …

Aim: Apelin, an adipocyte-derived factor, exhibited a number of cardioprotective properties;
however, its effect in diabetes which is a major risk factor for cardiovascular disease (CVD) …

Objective (s) Apelin is novel adipokine acting on APJ receptor, regulated by insulin and
tumor necrosis factor-alpha (TNF-alpha). Plasma apelin levels are increased in obese …