Therapeutics for Clostridioides difficile infection: molecules and microbes

S Khanna, E Voth - Expert Review of Gastroenterology & …, 2023 - Taylor & Francis
Introduction Clostridioides difficile infection (CDI) is a major healthcare problem in the
developed world, and effective management of recurrent infection remains one of the …

Fighting against Clostridioides difficile infection: Current medications

M Quan, X Zhang, Q Fang, X Lv, X Wang… - International Journal of …, 2024 - Elsevier
Clostridioides difficile (formerly Clostridium difficile) has been regarded as an" urgent threat"
and a significant global health problem, as life-threatening diarrhea and refractory …

Investigational Treatment Agents for Recurrent Clostridioides difficile Infection (rCDI)

R Kullar, MCN Tran, EJC Goldstein - Journal of Experimental …, 2020 - Taylor & Francis
Clostridioides difficile infection (CDI) is a major cause of nosocomial diarrhea that is deemed
a global health threat. C. difficile strain BI/NAP1/027 has contributed to the increase in the …

[HTML][HTML] Frontiers in antibiotic alternatives for Clostridioides difficile infection

M Phanchana, P Harnvoravongchai… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Clostridioides difficile (C. difficile) is a gram-positive, anaerobic spore-forming bacterium and
a major cause of antibiotic-associated diarrhea. Humans are naturally resistant to C. difficile …

Recurrent Clostridioides difficile Infection: Current Clinical Management and Microbiome-Based Therapies

P Berry, S Khanna - BioDrugs, 2023 - Springer
Clostridioides difficile is one of the most important causes of healthcare-associated diarrhea.
The high incidence and recurrence rates of C. difficile infection, as well as its associated …

[HTML][HTML] Advances in Clostridioides difficile therapeutics

S Khanna - Expert Review of Anti-infective Therapy, 2021 - Taylor & Francis
Clostridioides difficile is an urgent public health threat by virtue of being the most common
pathogen in hospitals and an increased risk of community-acquired infection [1]. The …

[HTML][HTML] Controversies in the Prevention and Treatment of Clostridioides difficile Infection in Adults: A Narrative Review

TB Bainum, KR Reveles, RG Hall, K Cornell… - Microorganisms, 2023 - mdpi.com
Clostridioides difficile remains a problematic pathogen resulting in significant morbidity and
mortality, especially for high-risk groups that include immunocompromised patients. Both the …

Prevention and treatment of recurrent Clostridioides difficile infection

JH Shin, CA Warren - Current opinion in infectious diseases, 2019 - journals.lww.com
Prevention and treatment of recurrent Clostridioides diffici... : Current Opinion in Infectious
Diseases Prevention and treatment of recurrent Clostridioides difficile infection : Current Opinion …

Evolution of clinical guidelines for antimicrobial management of Clostridioides difficile infection

A Chaar, P Feuerstadt - Therapeutic advances in …, 2021 - journals.sagepub.com
Clostridioides difficile infection (CDI) has been an epidemic for many years. Our biggest
challenge in treating CDI is preventing recurrence, which is seen in approximately 25% of …

Clostridioides Difficile: A Concise Review of Best Practices and Updates

A Yakout, Y Bi, DM Harris - Journal of Primary Care & …, 2024 - journals.sagepub.com
Clostridioides difficile infection (CDI) is one of the most common and severe nosocomial
infections worldwide. It can also affect healthy individuals in the community. The incidence of …