The recently discovered type III interferons (IFNs), also known as IFN-λ, are part of the early
innate immune response against viral infections. The IFN-λ system closely resembles the …

Coronavirus disease 2019 (COVID‐19), triggered by the betacoronavirus SARS‐CoV‐2, has
become one of the worst pandemics of our time that has already caused more than 250,000 …

For a long time, the family of type I interferons (IFN‐α/β) has received little attention outside
the fields of virology and tumor immunology. In recent years, IFN‐α/β regained the interest of …

Abstract Interferon-lambda (IFN-λ), a recently discovered cytokine, overlaps broadly with
type I IFN signaling, producing antiviral, antiproliferative, and proapoptotic responses. In …

Recent findings concerning the biology of IFN-λs and their pathophysiological roles in viral
infection, cancer, and immune responses of the innate and adaptive arms are summarized …

The recently discovered IFN‐λ4 has been found to have antiviral activity against several
viruses. However, it's unknown whether IFN‐λ4 can inhibit HIV infection. Here, we show that …

Type I interferons (IFN-α/β) and the more recently identified type III IFNs (IFN-λ) function as
the first line of defense against virus infection and regulate the development of both innate …

The interferons (IFNs) are a primary defense against pathogens because of the strong
antiviral activities they induce. IFNs can be classified into three groups: type I, type II and …

During most viral infections, the immediate host response is characterized by an induction of
type I IFN. These cytokines have various biological activities, including anti‐viral, anti …

Lambda interferons (IFN-λs), type III interferons or interleukins 28 and 29 are the latest
addition to the class II cytokine family. They share low homology with the interferon (IFN) and …