Classically, the nucleotide excision repair (NER) of cyclobutane pyrimidine dimers (CPD) is
a lengthy process (t 1/2> 48 h). Using the T4 endonuclease V-modified comet assay, we …

Absorption of solar ultraviolet (UV) radiation by DNA leads to the formation of the highly
mutagenic cyclobutane pyrimidine dimer (CPD). The mutagenicity of CPD is caused, in part …

Absorption of UV rays by DNA generates the formation of mutagenic cyclobutane pyrimidine
dimers (CPD) and pyrimidine (6–4) pyrimidone photoproducts (6-4PP). These damages are …

Abstract UVA light (320-400 nm) represents approximately 95% of the total solar UV
radiation that reaches the Earth's surface. UVA light induces oxidative stress and the …

UV‐induced formation of pyrimidine dimers in DNA is a major deleterious event in both
eukaryotic and prokaryotic cells. Accumulation of cyclobutane pyrimidine dimers and …

Ultraviolet (UV) radiation is one of the most genotoxic, universal agents present in the
environment. UVB (280-315 nm) radiation directly damages DNA, producing cyclobutane …

Photolyase transgenic mice have opened new avenues to improve our understanding of the
cytotoxic effects of ultraviolet (UV) light on skin by providing a means to selectively remove …

Ultraviolet (UV) irradiation induces helix distorting photolesions such as cyclobutane
pyrimidine dimers (CPD) and pyrimidine-pyrimidone (6-4) photoproducts (6-4PP) which …

We investigated the relationship between nucleotide excision repair (NER) activity and
apoptosis in UV-irradiated cells. Mouse erythroleukemia (MEL) and lymphoma (GRSL) cells …

Nicotinamide (vitamin B3) protects from ultraviolet (UV) radiation-induced carcinogenesis in
mice and from UV-induced immunosuppression in mice and humans. Recent double …