[HTML][HTML] Persistent malfunction of glymphatic and meningeal lymphatic drainage in a mouse model of subarachnoid hemorrhage

T Pu, W Zou, W Feng, Y Zhang, L Wang… - Experimental …, 2019 - ncbi.nlm.nih.gov
Subarachnoid hemorrhage (SAH) is a devastating cerebrovascular event that often is
followed by permanent brain impairments. It is necessary to explore the pathogenesis of …

The regulation of cerebral spinal fluid flow and its relevance to the glymphatic system

CD McKnight, RM Rouleau, MJ Donahue… - Current neurology and …, 2020 - Springer
Abstract Purpose of Review The glymphatic system is a relatively new concept that has been
associated with regulation of cerebrospinal fluid (CSF), as well as brain waste clearance …

Imaging the neurovascular unit in health and neurodegeneration: a scoping review of interdependencies between MRI measures

E Rowsthorn, W Pham, MR Nazem-Zadeh… - Fluids and Barriers of …, 2023 - Springer
The neurovascular unit (NVU) is a complex structure that facilitates nutrient delivery and
metabolic waste clearance, forms the blood–brain barrier (BBB), and supports fluid …

The lymphatic drainage system of the CNS plays a role in lymphatic drainage, immunity, and neuroinflammation in stroke

J Chen, L Wang, H Xu, Y Wang… - Journal of Leukocyte …, 2021 - academic.oup.com
The lymphatic drainage system of the central nervous system (CNS) plays an important role
in maintaining interstitial fluid balance and regulating immune responses and immune …

Chronic cerebrovascular dysfunction after traumatic brain injury

A Jullienne, A Obenaus, A Ichkova… - Journal of …, 2016 - Wiley Online Library
Traumatic brain injuries (TBI) often involve vascular dysfunction that leads to long‐term
alterations in physiological and cognitive functions of the brain. Indeed, all the cells that form …

Neuroimmune cleanup crews in brain injury

AC Bolte, JR Lukens - Trends in immunology, 2021 - cell.com
Traumatic brain injury (TBI) is a leading cause of death and disability. Mounting evidence
indicates that the immune system is critically involved in TBI pathogenesis, where it is …

Sleep and perivascular spaces

BK Dredla, OH Del Brutto, PR Castillo - Current neurology and …, 2023 - Springer
Abstract Purpose of Review The glymphatic system is hypothesized to act as the brain's
filtration system to remove toxic solutes that accumulate throughout the day. Perivascular …

Cerebrospinal fluid efflux through dynamic paracellular pores on venules as a missing piece of the brain drainage system

Y Dong, T Xu, L Yuan, Y Wang, S Yu, Z Wang… - …, 2024 - Wiley Online Library
The glymphatic system plays a key role in the clearance of waste from the parenchyma, and
its dysfunction has been associated with the pathogenesis of Alzheimer's disease (AD) …

Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer

L Yang, BT Kress, HJ Weber, M Thiyagarajan… - Journal of translational …, 2013 - Springer
Background Neurodegenerative diseases such as Alzheimer's are associated with the
aggregation of endogenous peptides and proteins that contribute to neuronal dysfunction …

Assessment of factors influencing glymphatic activity and implications for clinical medicine

A Gędek, D Koziorowski, S Szlufik - Frontiers in Neurology, 2023 - frontiersin.org
The glymphatic system is a highly specialized fluid transport system in the central nervous
system. It enables the exchange of the intercellular fluid of the brain, regulation of the …