A Cytosolic Arabidopsis d-Xylulose Kinase Catalyzes the Phosphorylation of 1-Deoxy-d-Xylulose into a Precursor of the Plastidial Isoprenoid Pathway

A Hemmerlin, D Tritsch, M Hartmann, K Pacaud… - Plant …, 2006 - academic.oup.com
Plants are able to integrate exogenous 1-deoxy-d-xylulose (DX) into the 2 C-methyl-d-
erythritol 4-phosphate pathway, implicated in the biosynthesis of plastidial isoprenoids …

Functional characterization of the three genes encoding 1-deoxy-D-xylulose 5-phosphate synthase in maize

E Cordoba, H Porta, A Arroyo… - Journal of …, 2011 - academic.oup.com
Abstract The 1-deoxy-d-xylulose 5-phosphate synthase (DXS) enzyme catalyses the first
biosynthetic step of the 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway. In plants the …

Two distantly related genes encoding 1‐deoxy‐d‐xylulose 5‐phosphate synthases: differential regulation in shoots and apocarotenoid‐accumulating mycorrhizal …

MH Walter, J Hans, D Strack - The Plant Journal, 2002 - Wiley Online Library
Isopentenyl diphosphate, the universal precursor of isoprenoids, is synthesized by two
separate routes, one in the cytosol and the other in plastids. The initial step of the plastidial …

Analysis of the Expression of CLA1, a Gene That Encodes the 1-Deoxyxylulose 5-Phosphate Synthase of the 2-C-Methyl-d-Erythritol-4-Phosphate Pathway in …

JM Estévez, A Cantero, C Romero, H Kawaide… - Plant …, 2000 - academic.oup.com
The discovery of the 2-C-methyl-d-erythritol-4-phosphate pathway for the biosynthesis of
isoprenoids raises the important question of the nature and regulation of the enzymes …

Temperature‐sensitive Arabidopsis mutant defective in 1‐deoxy‐d‐xylulose 5‐phosphate synthase within the plastid non‐mevalonate pathway of isoprenoid …

N Araki, K Kusumi, K Masamoto, Y Niwa… - Physiologia …, 2000 - Wiley Online Library
The temperature‐sensitive mutant of Arabidopsis, chs5, developed chlorotic leaves at
restrictive temperatures (15° C), but almost normal green leaves at permissive temperatures …

Functional and evolutionary analysis of DXL1, a non-essential gene encoding a 1-deoxy-D-xylulose 5-phosphate synthase like protein in Arabidopsis thaliana

L Carretero-Paulet, A Cairó, D Talavera, A Saura… - Gene, 2013 - Elsevier
The synthesis of 1-deoxy-D-xylulose 5-phosphate (DXP), catalyzed by the enzyme DXP
synthase (DXS), represents a key regulatory step of the 2-C-methyl-D-erythritol 4-phosphate …

1-Deoxy-D-xylulose-5-phosphate synthase, a limiting enzyme for plastidic isoprenoid biosynthesis in plants

JM Estévez, A Cantero, A Reindl, S Reichler… - Journal of Biological …, 2001 - ASBMB
The initial step of the plastidic 2C-methyl-d-erythritol 4-phosphate (MEP) pathway that
produces isopentenyl diphosphate is catalyzed by 1-deoxy-d-xylulose-5-phosphate …

Reassessing the evolution of the 1-deoxy-D-xylulose 5-phosphate synthase family suggests a possible novel function for the DXS class 3 proteins

L de Luna-Valdez, M Chenge-Espinosa… - Plant Science, 2021 - Elsevier
Abstract The methylerythritol 4-phosphate (MEP) pathway is of paramount importance for
generating plastidial isoprenoids. The first enzyme of the MEP pathway, 1-deoxy-D-xylulose …

Exploring the Deoxy-D-xylulose-5-phosphate Synthase Gene Family in Tomato (Solanum lycopersicum)

X Di, M Rodriguez-Concepcion - Plants, 2023 - mdpi.com
Isoprenoids are a wide family of metabolites including high-value chemicals, flavors,
pigments, and drugs. Isoprenoids are particularly abundant and diverse in plants. The …

Cytidine 5′-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol

F Rohdich, J Wungsintaweekul… - Proceedings of the …, 1999 - National Acad Sciences
2-C-methylerythritol 4-phosphate has been established recently as an intermediate of the
deoxyxylulose phosphate pathway used for biosynthesis of terpenoids in plants and in many …