The gastrointestinal (GI) tract is a major target in graft-versus-host disease (GvHD). In
rodents both tumor necrosis factor (TNF) and Fas-dependent apoptosis have been shown to …

Background & Aims: Gut graft-versus-host disease (GVHD) contributes significantly to
lethality after allogeneic hematopoietic stem-cell transplantation (HSCT). In murine models …

Donor T cells are crucial for target organ injury in graft‐versus‐host disease (GVHD). We
examined the effects of donor T cells on the target organs using a parent‐into‐F1 model of …

The pathophysiology of acute graft-versus-host disease (GVHD) is a complex process that
can be conceptualized in three phases. In the first phase, high-dose chemoradiotherapy …

BACKGROUND Murine T cell mediated acute semiallogeneic graft versus host disease
(GVHD) is characterised by lymphocytic infiltrates, crypt hyperplasia, and villous atrophy. It …

Summary (C57BL/6× DBA/2) F1‐hybrid mice injected with lymphoid cells from wild‐type,
C57BL/6 donors develop acute, lethal graft‐versus‐host disease (GVHD) in which the …

Low-grade lesions of graft-versus-host disease (GVHD) in the colon are not uncommon. To
determine if minimal diagnostic criteria can be established in such biopsies, we correlated …

Allogeneic haematopoietic stem cell transplantation remains the treatment of choice for a
number of malignancies. However, graft-versus-host disease (GVHD) has long been …

Acute graft-versus-host disease is a common complication of allogeneic bone marrow
transplantation, but the mechanisms resulting in tissue injury are uncertain. In order to probe …

Graft-versus-host disease (GVHD) can be acute or chronic. The pathogenesis of chronic
GVHD is unclear. Chronic GVHD affects mainly skin, liver and digestive tract. Intestinal …