Digital medicine: a primer on measurement

A Coravos, JC Goldsack, DR Karlin, C Nebeker… - Digital …, 2019 - karger.com
Technology is changing how we practice medicine. Sensors and wearables are getting
smaller and cheaper, and algorithms are becoming powerful enough to predict medical …

Digital biomarkers: convergence of digital health technologies and biomarkers

S Vasudevan, A Saha, ME Tarver, B Patel - NPJ digital medicine, 2022 - nature.com
Increasing digitization across the healthcare continuum has revolutionized medical
research, diagnostics, and therapeutics. This digitization has led to rapid advancements in …

Developing and adopting safe and effective digital biomarkers to improve patient outcomes

A Coravos, S Khozin, KD Mandl - NPJ digital medicine, 2019 - nature.com
Biomarkers are physiologic, pathologic, or anatomic characteristics that are objectively
measured and evaluated as an indicator of normal biologic processes, pathologic …

Digital medicine, on its way to being just plain medicine

SR Steinhubl, EJ Topol - NPJ digital Medicine, 2018 - nature.com
To answer that question, we need to begin by defining what “digital medicine” means: using
digital tools to upgrade the practice of medicine to one that is high-definition and far more …

Digital measures that matter to patients: a framework to guide the selection and development of digital measures of health

C Manta, B Patrick-Lake, JC Goldsack - Digital Biomarkers, 2020 - karger.com
Background: With the rise of connected sensor technologies, there are seemingly endless
possibilities for new ways to measure health. These technologies offer researchers and …

Digital health: a path to validation

SC Mathews, MJ McShea, CL Hanley, A Ravitz… - NPJ digital …, 2019 - nature.com
Digital health solutions continue to grow in both number and capabilities. Despite these
advances, the confidence of the various stakeholders—from patients and clinicians to …

Verification, analytical validation, and clinical validation (V3): the foundation of determining fit-for-purpose for Biometric Monitoring Technologies (BioMeTs)

JC Goldsack, A Coravos, JP Bakker, B Bent… - npj digital …, 2020 - nature.com
Digital medicine is an interdisciplinary field, drawing together stakeholders with expertize in
engineering, manufacturing, clinical science, data science, biostatistics, regulatory science …

Evaluation, acceptance, and qualification of digital measures: from proof of concept to endpoint

JC Goldsack, AV Dowling, D Samuelson… - Digital …, 2021 - karger.com
To support the successful adoption of digital measures into internal decision making and
evidence generation for medical product development, we present a unified lexicon to aid …

Translational gaps and opportunities for medical wearables in digital health

S Xu, J Kim, JR Walter, R Ghaffari… - Science translational …, 2022 - science.org
A confluence of advances in biosensor technologies, enhancements in health care delivery
mechanisms, and improvements in machine learning, together with an increased awareness …

Digital health—the need to assess benefits, risks, and value

E Perakslis, GS Ginsburg - Jama, 2021 - jamanetwork.com
Digitalhealthisabroadspectrumofmeasurem…-nologies that include personal wearable
devices and internal devices as well as sensors in people, homes, cars, and communities …