Antibody-mediated neutralization of SARS-CoV-2
Neutralizing antibodies can block infection, clear pathogens, and are essential to provide
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …
A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
T Noy-Porat, E Makdasi, R Alcalay, A Mechaly… - Nature …, 2020 - nature.com
The novel highly transmissible human coronavirus SARS-CoV-2 is the causative agent of
the COVID-19 pandemic. Thus far, there is no approved therapeutic drug specifically …
the COVID-19 pandemic. Thus far, there is no approved therapeutic drug specifically …
Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants
Neutralizing antibodies elicited by prior infection or vaccination are likely to be key for future
protection of individuals and populations against SARS-CoV-2. Moreover, passively …
protection of individuals and populations against SARS-CoV-2. Moreover, passively …
Structural and functional analysis of a potent sarbecovirus neutralizing antibody
SARS-CoV-2 is a newly emerged coronavirus responsible for the current COVID-19
pandemic that has resulted in more than one million infections and 73,000 deaths,. Vaccine …
pandemic that has resulted in more than one million infections and 73,000 deaths,. Vaccine …
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model
Countermeasures to prevent and treat coronavirus disease 2019 (COVID-19) are a global
health priority. We enrolled a cohort of severe acute respiratory syndrome coronavirus 2 …
health priority. We enrolled a cohort of severe acute respiratory syndrome coronavirus 2 …
Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2
X Rao, R Zhao, Z Tong, S Guo… - Proceedings of the …, 2023 - National Acad Sciences
Currently, monoclonal antibodies (MAbs) targeting the SARS-CoV-2 receptor binding
domain (RBD) of spike (S) protein are classified into seven classes based on their binding …
domain (RBD) of spike (S) protein are classified into seven classes based on their binding …
Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability
PJM Brouwer, TG Caniels, K van der Straten… - Science, 2020 - science.org
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
had a large impact on global health, travel, and economy. Therefore, preventative and …
had a large impact on global health, travel, and economy. Therefore, preventative and …
SARS-CoV-2 neutralizing human antibodies protect against lower respiratory tract disease in a hamster model
Effective clinical intervention strategies for coronavirus disease 2019 (COVID-19) are
urgently needed. Although several clinical trials have evaluated use of convalescent plasma …
urgently needed. Although several clinical trials have evaluated use of convalescent plasma …
Extremely potent human monoclonal antibodies from COVID-19 convalescent patients
Human monoclonal antibodies are safe, preventive, and therapeutic tools that can be rapidly
developed to help restore the massive health and economic disruption caused by the …
developed to help restore the massive health and economic disruption caused by the …
SARS-CoV-2 variants B. 1.351 and B. 1.1. 248: Escape from therapeutic antibodies and antibodies induced by infection and vaccination
M Hoffmann, P Arora, R Groß, A Seidel, B Hörnich… - BioRxiv, 2021 - biorxiv.org
The global spread of SARS-CoV-2/COVID-19 is devastating health systems and economies
worldwide. Recombinant or vaccine-induced neutralizing antibodies are used to combat the …
worldwide. Recombinant or vaccine-induced neutralizing antibodies are used to combat the …