Current strategies in tailoring methods for engineered exosomes and future avenues in biomedical applications

A Mishra, P Singh, I Qayoom, A Prasad… - Journal of Materials …, 2021 - pubs.rsc.org
Exosomes are naturally occurring nanovesicles of endosomal origin, responsible for cellular
communication. Depending on the cell type, exosomes display disparity in the cargo and are …

Engineered exosomes for tissue regeneration: from biouptake, functionalization, biosafety to applications

M Zhang, L Wan, R Li, X Li, T Zhu, H Lu - Biomaterials Science, 2023 - pubs.rsc.org
Exosomes are increasingly recognized as important effector molecules that regulate
intercellular signaling pathways. Notably, certain types of exosomes can induce therapeutic …

Surface engineering of extracellular vesicles through chemical and biological strategies

JJ Richardson, H Ejima - Chemistry of Materials, 2019 - ACS Publications
Extracellular vesicles, including exosomes, shuttle proteins and genetic information between
cells and are recently regarded as a promising class of nanoparticles for biomedical …

Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications

J Mondal, S Pillarisetti, V Junnuthula, M Saha… - Journal of Controlled …, 2023 - Elsevier
Exosomes are endosome-derived nanovesicles involved in cellular communication. They
are natural nanocarriers secreted by various cells, making them suitable candidates for …

Bioinspired exosome-like therapeutics and delivery nanoplatforms

M Lu, Y Huang - Biomaterials, 2020 - Elsevier
Exosomes have emerged as appealing candidate therapeutic agents and delivery
nanoplatforms due to their endogenous features and unique biological properties. However …

Exosomes engineering and their roles as therapy delivery tools, therapeutic targets, and biomarkers

N Kučuk, M Primožič, Ž Knez, M Leitgeb - International journal of …, 2021 - mdpi.com
Exosomes are becoming increasingly important therapeutic biomaterials for use in a variety
of therapeutic applications due to their unique characteristics, especially due to the …

Optimization of exosome-based cell-free strategies to enhance endogenous cell functions in tissue regeneration

S Deng, H Cao, X Cui, Y Fan, Q Wang, X Zhang - Acta Biomaterialia, 2023 - Elsevier
Exosomes, nanoscale extracellular vesicles, play a crucial role in intercellular
communication, owing to their biologically active cargoes such as RNAs and proteins. In …

Engineered exosomes: a promising vehicle in cancer therapy

F Pooresmaeil, S Andi, B Hasannejad-Asl… - Therapeutic …, 2023 - Taylor & Francis
During the past few decades, researchers have attempted to discover an effective treatment
for cancer. Exosomes are natural nanovesicles released by various cells and play a role in …

Engineering Approaches for Exosome Cargo Loading and Targeted Delivery: Biological versus Chemical Perspectives

W Ahmed, A Mushtaq, S Ali, N Khan… - ACS Biomaterials …, 2024 - ACS Publications
Exosomes are nanoscale membrane bound vesicles secreted by almost all types of cells.
Their unique attributes, such as minimal immunogenicity and compatibility with biological …

Therapeutic strategies and enhanced production of stem cell-derived exosomes for tissue regeneration

H Kim, D Kim, W Kim, S Lee, Y Gwon… - … Engineering Part B …, 2023 - liebertpub.com
Exosomes are nanovesicles surrounded by a plasma membrane and carry bioactive
molecules (eg, proteins, lipids, and nucleic acids) of the origin cell type. The bioactive …