Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

M Catanzaro, F Fagiani, M Racchi, E Corsini… - Signal transduction and …, 2020 - nature.com
To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19
and the current standard care relies on supportive treatments. Therefore, based on the fast …

COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
The recent novel coronavirus disease (COVID-19) outbreak, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is seeing a rapid increase in infected …

[HTML][HTML] Mechanistic insights into the immune pathophysiology of COVID-19; an in-depth review

A Shafqat, S Shafqat, SA Salameh, J Kashir… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …

Diverse immunological factors influencing pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter cytokine …

AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …

COVID-19: immunology, immunopathogenesis and potential therapies

A Bhardwaj, L Sapra, C Saini, Z Azam… - International reviews …, 2022 - Taylor & Francis
Abstract The Coronavirus Disease-2019 (COVID-19) imposed public health emergency and
affected millions of people around the globe. As of January 2021, 100 million confirmed …

Immunobiology and immunotherapy of COVID‐19: A clinically updated overview

A Esmaeilzadeh, R Elahi - Journal of cellular physiology, 2021 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a new member of the
coronavirus family that can cause coronavirus disease 2019 (COVID‐19). COVID‐9 has …

Innate immune response to SARS-CoV-2 infection: From cells to soluble mediators

D Ricci, MP Etna, F Rizzo, S Sandini, M Severa… - International journal of …, 2021 - mdpi.com
The vulnerability of humankind to SARS-CoV-2 in the absence of a pre-existing immunity,
the unpredictability of the infection outcome, and the high transmissibility, broad tissue …

[HTML][HTML] Recent insight into SARS-CoV2 immunopathology and rationale for potential treatment and preventive strategies in COVID-19

S Lega, S Naviglio, S Volpi, A Tommasini - Vaccines, 2020 - mdpi.com
As the outbreak of the new coronavirus (SARS-CoV-2) infection is spreading globally, great
effort is being made to understand the disease pathogenesis and host factors that …

Immune responses in mildly versus critically ill COVID-19 patients

H Nasrollahi, AG Talepoor, Z Saleh… - Frontiers in …, 2023 - frontiersin.org
The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had
devastating effects on the global health and economic system. The cellular and molecular …

[PDF][PDF] Immunology of COVID-19: current state of the science

N Vabret, GJ Britton, C Gruber, S Hegde, J Kim… - Immunity, 2020 - cell.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting …