Association between serotonin transporter gene promoter polymorphism (5HTTLPR) and behavioral responses to tryptophan depletion in healthy women with and …

A Neumeister, A Konstantinidis, J Stastny… - Archives of general …, 2002 - jamanetwork.com
Background Evidence suggests that serotonin transporter gene promoter polymorphism
(5HTTLPR)–dependent low transcriptional activity of the human serotonin transporter gene …

The 5‐HTTLPR s/s genotype at the serotonin transporter gene (SLC6A4) increases the risk for depression in a large cohort of primary care attendees: the PREDICT …

JA Cervilla, M Rivera, E Molina… - American Journal of …, 2006 - Wiley Online Library
Previous reports and meta‐analyses have yielded inconclusive results as to whether the s/s
genotype at the 5‐HTTLPR serotonin transporter polymorphism confers increased risk for …

[HTML][HTML] Interaction of serotonin transporter gene-linked polymorphic region and stressful life events predicts cortisol stress response

A Mueller, D Armbruster, DA Moser, T Canli… - …, 2011 - nature.com
There has been significant controversy whether stressful life events (SLEs) experienced
over the lifespan may elevate the risk of depression in individuals who are homozygous for …

Serotonin transporter gene, childhood emotional abuse and cognitive vulnerability to depression

N Antypa, AJW Van der Does - Genes, Brain and Behavior, 2010 - Wiley Online Library
Meta‐analyses evaluating the association between the serotonin transporter polymorphism
(5‐HTTLPR) with neuroticism and depression diagnosis as phenotypes have been …

[HTML][HTML] Serotonin transporter 5HTTLPR polymorphism and affective disorders: no evidence of association in a large European multicenter study

J Mendlewicz, I Massat, D Souery… - European Journal of …, 2004 - nature.com
The available data from preclinical and pharmacological studies on the role of the serotonin
transporter (5-HTT) support the hypothesis that a dysfunction in brain serotonergic system …

Gene–environment interactions predict cortisol responses after acute stress: implications for the etiology of depression

N Alexander, Y Kuepper, A Schmitz, R Osinsky… - …, 2009 - Elsevier
BACKGROUND: Growing evidence suggests that the serotonin transporter polymorphism (5-
HTTLPR) interacts with adverse environmental influences to produce an increased risk for …

Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations

P Xie, HR Kranzler, J Poling, MB Stein… - Archives of general …, 2009 - jamanetwork.com
Context The5-HTTLPRpolymorphism in the promoter region of the serotonin transporter
gene (SLC6A4) has been found to moderate several categories of emotional response after …

Stress-related negative affectivity and genetically altered serotonin transporter function: evidence of synergism in shaping risk of depression

N Jacobs, G Kenis, F Peeters, C Derom… - Archives of general …, 2006 - jamanetwork.com
Context Genetic moderation of the depression-inducing effects of stressful life events (SLEs)
has been reported, but findings suggest that genes may not moderate the effects of SLEs per …

Antidepressant response and the serotonin transporter gene-linked polymorphic region

MJ Taylor, S Sen, Z Bhagwagar - Biological psychiatry, 2010 - Elsevier
BACKGROUND: The serotonin transporter gene-linked polymorphic region (5-HTTLPR) has
been proposed as a predictor of antidepressant response. Insertion or deletion of a 44-base …

Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression

G Zalsman, Y Huang, MA Oquendo… - American journal of …, 2006 - Am Psychiatric Assoc
Objective: The lower expressing allele of the serotonin transporter gene 5′ promoter region
(5-HTTLPR) polymorphism is reported to be associated with susceptibility to depression and …