cfOmics: a cell-free multi-Omics database for diseases

M Li, T Zhou, M Han, H Wang, P Bao… - Nucleic Acids …, 2024 - academic.oup.com
Liquid biopsy has emerged as a promising non-invasive approach for detecting, monitoring
diseases, and predicting their recurrence. However, the effective utilization of liquid biopsy …

Multiomic Approaches for Cancer Biomarker Discovery in Liquid Biopsies: Advances and Challenges

PM Diaz, A Leehans, P Ravishankar… - Biomarker …, 2023 - journals.sagepub.com
Cancer is a complex and heterogeneous disease that poses a significant threat to global
health. Early diagnosis and treatment are critical for improving patient outcomes, and the …

Mining nucleic acid “omics” to boost liquid biopsy in cancer

A Tivey, RJ Lee, A Clipson, SM Hill, P Lorigan… - Cell Reports …, 2024 - cell.com
Treatments for cancer patients are becoming increasingly complex, and there is a growing
desire from clinicians and patients for biomarkers that can account for this complexity to …

The translational status of cancer liquid biopsies

S Bratulic, F Gatto, J Nielsen - Regenerative Engineering and …, 2021 - Springer
Precision oncology aims to tailor clinical decisions specifically to patients with the objective
of improving treatment outcomes. This can be achieved by leveraging omics information for …

Liquid biopsy in oncology: opportunity and challenges

A Kumar, R Singh, N Arya, S Lueong… - Frontiers in Molecular …, 2024 - frontiersin.org
Despite significant advances in cancer diagnosis and treatment, cancer remains one of the
major causes of mortality worldwide. Current challenges in cancer management include …

An Old Concept with a New Twist

YH Su - Genetic testing and molecular biomarkers, 2019 - liebertpub.com
Aliquid biopsy is a simple noninvasive alternative to tissue biopsies in which a body fluid
specimen is obtained for detailed laboratory analyses. Tissue biopsy has been used to …

Liquid biopsies beyond mutation calling: genomic and epigenomic features of cell-free DNA in cancer

AK Angeles, F Janke, S Bauer, P Christopoulos… - Cancers, 2021 - mdpi.com
Simple Summary Liquid biopsies provide a non-invasive means to diagnose and profile
tumors when tissue is not available. Sequence-based analysis of cell-free DNA (cfDNA) is …

cfDNApipe: a comprehensive quality control and analysis pipeline for cell-free DNA high-throughput sequencing data

W Zhang, L Wei, J Huang, B Zhong, J Li, H Xu… - …, 2021 - academic.oup.com
Abstract Motivation Cell-free DNA (cfDNA) is gaining substantial attention from both
biological and clinical fields as a promising marker for liquid biopsy. Many aspects of …

Liquid biopsy for precision diagnostics and therapeutics

K Anitha, B Posinasetty, KN Kumari, S Chenchula… - Clinica Chimica …, 2023 - Elsevier
Liquid biopsy (LB) has emerged as a highly promising and non-invasive diagnostic
approach, particularly in the field of oncology, and has garnered interest in various medical …

Proteomics technologies for cancer liquid biopsies

Z Ding, N Wang, N Ji, ZS Chen - Molecular Cancer, 2022 - Springer
Alterations in DNAs could not reveal what happened in proteins. The accumulated
alterations of DNAs would change the manifestation of proteins. Therefore, as is the case in …