Cerebral vasospasm after subarachnoid hemorrhage (SAH) is characterized by prolonged
severe constriction of the basilar artery, which often leads to ischemic brain damage. Locally …

BACKGROUND AND PURPOSE Cerebral vasospasm is the persistent constriction of large
conduit arteries in the base of the brain. This pathologically sustained contraction of the …

Delayed cerebral vasospasm after subarachnoid hemorrhage is primarily due to sustained
contraction of arterial smooth muscle cells. Its pathogenesis remains unclear. The degree of …

KCNQ gene expression was previously shown in various rodent blood vessels, where the
products of KCNQ4 and KCNQ5, Kv7. 4 and Kv7. 5 potassium channel subunits …

Background and purpose: This study represents a novel characterisation of KCNQ‐encoded
potassium channels in the vasculature using a variety of pharmacological and molecular …

Background and Purpose Kv7 (Kv7. 1–7.5) channels play an important role in the regulation
of neuronal excitability and the cardiac action potential. Growing evidence suggests Kv7 …

Background and Purpose The KCNQ‐encoded voltage‐gated potassium channel family (Kv
7.1‐Kv 7.5) are established regulators of smooth muscle contractility, where Kv 7.4 and Kv …

Cerebral vasospasm after subarachnoid hemorrhage (SAH) is because of smooth muscle
contraction, although the mechanism of this contraction remains unresolved. Membrane …

Alterations in the activity of vascular K+ channels are commonly associated with
abnormalities in cerebral vascular function after subarachnoid hemorrhage (SAH) …

Background and Purpose KV7. 1 voltage‐gated potassium channels are expressed in
vascular smooth muscle cells (VSMC) of diverse arteries, including mesenteric arteries …