Liver and biliary tract cancers are highly aggressive, are heterogeneous in their phenotypic
traits, and result in clinical outcomes that are difficult to manage. Cancers have …

Hepatocellular carcinoma (HCC) is the most commonly diagnosed malignancy of the liver
and is the third most frequent cause of cancer death worldwide. Although advances in HCC …

Liver cancer is an aggressive disease with a poor outcome. Several hepatic stem/progenitor
markers are useful for isolating a subset of liver cells with stem cell features, known as …

It is widely accepted that cancer is a disease of stem cells. Definite evidence suggests that
tumors harbor a small population of cancer stem cells (CSC) that both give rise to the bulk of …

There has been considerable interest in cancer stem cells (CSCs) among cancer biologists
and clinicians, most likely because of their role in the heterogeneity of cancer and their …

Although the existence of cancer stem cells (CSCs) was first proposed over 40 years ago,
only in the past decade have these cells been identified in hematological malignancies, and …

Hepatocellular carcinoma (HCC) is an aggressive tumour with a poor prognosis. Current
therapeutic strategies against this disease target mostly rapidly growing differentiated …

Background & Aims: Recent efforts in stem cell biology suggest that tumors are organized in
a hierarchy of heterogeneous cell populations and that the capability to maintain tumor …

Background Hepatocellular carcinoma is one of the most common cancers and the second
leading cause of cancer-related deaths worldwide. Only a small proportion of patients …

Hepatocellular carcinoma (HCC) is an aggressive disease with a poor clinical outcome. The
cancer stem cell (CSC) model states that tumour growth is powered by a subset of tumour …