Many central nervous system infections are historically difficult to diagnose. Polymerase
chain reaction (PCR) has revolutionized the diagnosis of these infections because of their …

The cerebrospinal fluid (CSF) polymerase chain reaction (PCR) is the gold standard to
detect cerebral viral activity. As positive findings do not prove an impact on the neurological …

Viruses are the leading cause of central nervous system (CNS) infections, ahead of bacteria,
parasites, and fungal agents. A rapid and comprehensive virologic diagnostic testing …

Background. Polymerase chain reaction (PCR) is becoming more common in diagnostic
laboratories. In some instances, its value has been established. In other cases, assays exist …

Background: Polymerase chain reaction (PCR) is used to detect viruses in the cerebrospinal
fluid (CSF) of patients with neurological disease. However, data to assist its use or …

Background Standard laboratory techniques, such as viral culture and serology, provide
only circumstantial or retrospective evidence of viral infections of the central nervous system …

The determination of herpes simplex virus (HSV) infection using a PCR assay is one of the
most commonly requested tests for analysis of cerebrospinal fluid (CSF), although only a …

Efficient and sensitive diagnostic methods are needed in the management of virus infections
in the central nervous system. There is a demand for an evaluation of the sensitivity of PCR …

Background Multiplex PCR panels are frequently used for detecting the diagnosis of central
nervous system infection, but have demonstrated lower sensitivity for herpes simplex virus …

Background: Infections of the central nervous system (CNS) are a difficult diagnostic
problem for both clinicians and microbiologists. Various clinical signs, such as encephalitis …