The highly homeostasis-resistant nature of cancer cells leads to their escape from treatment
and to liver metastasis, which in turn makes pancreatic ductal adenocarcinoma (PDAC) …

Pancreatic ductal adenocarcinoma (PDAC) adopts several unique metabolic strategies to
support primary tumor growth. Whether additional metabolic strategies are adopted to …

As one of the malignancies with high mortality and high insensitivity to existing therapies,
pancreatic cancer and mechanisms underlying its progression have received growing …

Pancreatic ductal adenocarcinoma (PDA) is characterized by a heterogenous and densely
fibrotic microenvironment. This limits functional vasculature and diffusion of nutrients through …

Background Pancreatic cancer is one of the most common malignancies worldwide. In
recent years, specific metabolic activities, which involves the development of tumor, caused …

The cytokine transforming growth factor-β (TGF-β) can induce normal breast epithelial cells
to take on a mesenchymal phenotype, termed epithelial-to-mesenchymal transition (EMT) …

Purpose Breast cancer is a heterogeneous disease with several subtypes that currently do
not have targeted therapeutic options. Metabolomics has the potential to uncover novel …

Metabolomics is a rapidly growing field of research used in the identification and
quantification of the small molecule metabolites within an organism, thereby providing …

Cancer-dependent metabolic rewiring is often manifested by selective expression of
enzymes essential for the transformed cells' viability. However, the metabolic variations …

Pancreatic neuroendocrine neoplasms (PanNENs) are a group of highly heterogeneous
neoplasms originating from the endocrine islet cells of the pancreas with characteristic …