Importance Although the usefulness of polygenic risk scores as a measure of genetic liability
for major depression (MD) has been established, their association with depression in the …

Background. Previous studies suggest that the relationship between genetic risk and
depression may be moderated by stressful life events (SLEs). The goal of this study was to …

Major depressive disorder (MDD) is a common psychiatric illness with high levels of
morbidity and mortality. Despite intensive research during the past several decades, the …

Importance We do not know whether the clinical criteria for major depression (MD) reflect a
single or multiple dimensions of genetic risk. Objective To determine the structure of genetic …

Compared with men, female accounts for a larger proportion of patients with depression.
Behavioral genetics researches find gender differences in genetic underpinnings of …

Major depressive disorder (MDD) is the most common psychiatric disorder and the second
overall cause of disability. Even though a significant amount of the variance in the MDD …

Depression is a group of brain disorders with varied origins, complex genetics and obscure
neurobiology. Definitions of clinical phenotypes are not rooted in their neurobiology, and …

Background The heterogeneity of genetic effects on major depressive disorder (MDD) may
be partly attributable to moderation of genetic effects by environment, such as exposure to …

Depressive disorders (DDs) are one of the most widespread forms of psychiatric pathology.
According to the World Health Organization, about 350 million people in the world are …

Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …